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C3416

羧苄青霉素二钠盐

Name: 羧苄青霉素 二钠盐
Brand: SIGMA

BioReagent, suitable for plant cell culture

别名:

α-Carboxybenzylpenicillin disodium salt 二钠盐

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About This Item

经验公式（希尔记法）:

C₁₇H₁₆N₂Na₂O₆S

CAS号:

4800-94-6

分子量:

422.36

Beilstein:

5722128

EC 号:

225-360-8

MDL编号:

MFCD00077683

UNSPSC代码:

51282413

PubChem化学物质编号:

24892613

NACRES:

NA.76

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Sigma-Aldrich

C1389

羧苄青霉素二钠盐

Sigma-Aldrich

C7039

Cefotaxime sodium salt 钠盐

Sigma-Aldrich

C1613

羧苄西林

Sigma-Aldrich

R3501

利福平

Millipore

205805

羧苄西林二钠盐

Sigma-Aldrich

A9518

氨苄西林钠盐

Sigma-Aldrich

C0378

氯霉素，大包装

Sigma-Aldrich

C9231

羧苄青霉素二钠

Supelco

69479

N-甲基-N-（三甲基硅烷基）三氟乙酰胺

Sigma-Aldrich

D0632

DL-二硫苏糖醇

产品线

BioReagent

质量水平

200

表单

powder

技术

cell culture | plant: suitable

溶解性

H₂O: 50 mg/mL

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria

应用

agriculture

作用机制

cell wall synthesis | interferes

储存温度

2-8°C

SMILES字符串

[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)c3ccccc3)C(=O)N2[C@H]1C([O-])=O

InChI

1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1

InChI key

RTYJTGSCYUUYAL-YCAHSCEMSA-L

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一般描述

Chemical structure: ß-lactam

应用

Recommended for antibacterial use in cell culture media at 100 μg/ml and for selection of ampr transformed cells.

生化/生理作用

作用机制：羧青霉素抗生素，可通过灭活细菌细胞膜内表面的转肽酶来抑制细菌细胞壁合成（肽聚糖交联）。

抗微生物谱：具有抗革兰氏阳性和革兰氏阴性细菌活性。

外形

Hygroscopic powder

分析说明

在 37°C 下可稳定保存 3 天

其他说明

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.

象形图

GHS08

警示用语：

Danger

危险声明

H317,H334

预防措施声明

P261 - P280 - P342 + P311

危险分类

Resp. Sens. 1 - Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

监管及禁止进口产品

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分析证书(COA)

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Inactivation of MuxABC-OpmB transporter system in Pseudomonas aeruginosa leads to increased ampicillin and carbenicillin resistance and decreased virulence.

Liang Yang et al.

Journal of microbiology (Seoul, Korea), 49(1), 107-114 (2011-03-04)

Resistance-Nodulation-Cell Division (RND) pumps play important roles in bacterial resistance to antibiotics. Pseudomonas aeruginosa is an important human pathogen which exhibits high level resistance to antibiotics. There are total of 12 RND pumps present in the P. aeruginosa PAOl genome.

Monamphilectine A, a potent antimalarial β-lactam from marine sponge Hymeniacidon sp: isolation, structure, semisynthesis, and bioactivity.

Edward Avilés et al.

Organic letters, 12(22), 5290-5293 (2010-10-23)

Monamphilectine A (1), a new diterpenoid β-lactam alkaloid showing potent antimalarial activity, was isolated in milligram quantities following bioassay-directed extraction of a Puerto Rican marine sponge Hymeniacidon sp. Its structure, established by interpretation of spectral data, was confirmed unequivocally by

Pseudomonas aeruginosa increases formation of multidrug-tolerant persister cells in response to quorum-sensing signaling molecules.

Nina Möker et al.

Journal of bacteriology, 192(7), 1946-1955 (2010-01-26)

Bacterial persister cells constitute a small portion of a culture which is tolerant to killing by lethal doses of bactericidal antibiotics. These phenotypic variants are formed in numerous bacterial species, including those with clinical relevance like the opportunistic pathogen Pseudomonas

Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms.

Sarah Sainsbury et al.

Journal of molecular biology, 405(1), 173-184 (2010-10-27)

We report the first crystal structures of a penicillin-binding protein (PBP), PBP3, from Pseudomonas aeruginosa in native form and covalently linked to two important β-lactam antibiotics, carbenicillin and ceftazidime. Overall, the structures of apo and acyl complexes are very similar;

Molecular dynamics of class A β-lactamases-effects of substrate binding.

Olivier Fisette et al.

Biophysical journal, 103(8), 1790-1801 (2012-10-23)

The effects of substrate binding on class A β-lactamase dynamics were studied using molecular dynamics simulations of two model enzymes; 40 100-ns trajectories of the free and substrate-bound forms of TEM-1 (with benzylpenicillin) and PSE-4 (with carbenicillin) were recorded (totaling

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主要文件

安全信息

羧苄青霉素 二钠盐

BioReagent, suitable for plant cell culture

About This Item

推荐产品

属性

产品线

质量水平

表单

技术

溶解性

抗生素抗菌谱

应用

作用机制

储存温度

SMILES字符串

InChI

InChI key

说明

一般描述

应用

生化/生理作用

外形

分析说明

其他说明

安全信息

象形图

警示用语：

危险声明

预防措施声明

危险分类

储存分类代码

WGK

闪点(°F)

闪点(°C)

个人防护装备

法规信息

文件

分析证书(COA)

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羧苄青霉素二钠盐