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应用
羰基氰化物间氯苯腙(CCCP)已用于：
- 抑制临床铜绿假单胞菌中的外排泵
- 抑制人Beas-2B支气管上皮细胞线粒体的氧化磷酸化活性
- 制备羰基氰化物间氯苯腙溶液，分析秀丽隐杆线虫的氧化和线粒体应激及线粒体诱导作用
生化/生理作用
羰基氰3-氯苯肼(CCCP)诱导哺乳动物细胞的有丝分裂吞噬。CCCP抑制少量电子传递链(ETC)蛋白的表达。线粒体中氧化磷酸化的质子载体(H+ 离子载体)和解耦体。表明对细胞钙有多种影响。抑制肝脂肪酶分泌，部分抑制pH梯度激活的刷状缘膜泡中Cl- 的摄取和Cl-/Cl- 交换活性。
警示用语：
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
个人防护装备
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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