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C1768

Cytarabine

≥90% (HPLC), crystalline, DNA replication inhibitor

别名:

(β-D-阿拉伯呋喃糖基)胞嘧啶, Ara-C, 胞嘧啶阿拉伯糖苷, 阿拉伯糖胞嘧啶, 阿糖胞嘧啶, 阿糖胞苷

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关于此项目

经验公式（希尔记法）:
C9H13N3O5
化学文摘社编号:
147-94-4
分子量:
243.22
NACRES:
NA.77
PubChem Substance ID:
24892435
UNSPSC Code:
12352200
EC Number:
205-705-9
MDL number:
MFCD00066487
Beilstein/REAXYS Number:
89175
Assay:
≥90% (HPLC)
Form:
crystalline
Quality level:
200
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产品名称

胞嘧啶 β-D-呋喃阿拉伯糖苷, crystalline, ≥90% (HPLC)

Quality Level

200

assay

≥90% (HPLC)

form

crystalline

storage temp.

2-8°C

SMILES string

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2O

InChI

1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7+,8-/m1/s1

InChI key

UHDGCWIWMRVCDJ-CCXZUQQUSA-N

Gene Information

human ... POLA1(5422), POLA2(23649), POLB(5423), POLD1(5424), POLD2(5425), POLD3(10714), POLD4(57804), POLE(5426), POLE2(5427), POLE3(54107), PRIM1(5557), PRIM2(5558)
mouse ... Cda(72269)

Biochem/physiol Actions

阿糖胞苷复合到 DNA 中后，可通过与导致 DNA 断裂的拓扑异构酶 I 形成可裂解复合物而抑制 DNA 的复制，但不会抑制 RNA 的合成。抗白血病制剂。

Features and Benefits

该化合物是细胞凋亡研究的特色产品。点击此处 ，查看更多细胞凋亡精选产品。想要了解有关生物活性小分子在其他研究领域应用的更多信息，请访问 sigma.com/discover-bsm。

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ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

pictograms

Health hazard
GHS08

signalword

Danger

Hazard Classifications

Muta. 1B - Repr. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000518471
0000518471
0000505207
0000505205
0000505204

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Cell cycle phases (G1, S, G2, M) regulate cell growth, DNA replication, and division in proliferating cells.

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Here we explore the applicability of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to a variety of amine-containing drugs. Efficient procedures have been developed for the synthesis of dipeptide and tetrapeptide amide prodrugs including N-acylation protocols of the exocyclic
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全球贸易项目编号

货号GTIN
C1768-500MG04061833468029
C1768-100MG04061833468005
C1768-5G04061833023846
C1768-1G04061833468012