形式
solid
质量水平
颜色
white
溶解性
H2O: 99.2 mg/mL
ethanol: insoluble
SMILES字符串
OC(=O)C1CN(CCCP(O)(O)=O)CCN1
InChI
1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15)
InChI key
CUVGUPIVTLGRGI-UHFFFAOYSA-N
基因信息
human ... GRIN1(2902) , GRIN2A(2903) , GRIN2B(2904) , GRIN2C(2905) , GRIN2D(2906) , GRINA(2907)
rat ... Grin2a(24409)
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应用
(±)-CPP可用作非竞争性NMDA受体拮抗剂:
- 研究其对小鼠血糖的影响作用
- 用于小鼠大脑切片的电生理记录
- 用于大鼠海马体锥体神经元的电生理记录
生化/生理作用
4-(3-膦酰丙基)哌嗪-2-羧酸(CPP)是强效、竞争性和选择性的N-甲基-D-天冬氨酸(NMDA)受体拮抗剂。它是2-氨基-7-膦酰庚酸的类似物。CPP具有抗惊厥和镇痛作用。
注意
吸湿
警示用语:
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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