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B7148

丁螺环酮盐酸盐 盐酸盐

≥99% (TLC), powder, 5-HT1A serotonin receptor agonist

别名:

N-[4-[4-(2-嘧啶基)-1-哌嗪基] 丁基]-8-氮杂螺[4.5]癸烷-7,9-二酮 盐酸盐

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关于此项目

经验公式（希尔记法）:
C21H31N5O2 · HCl
化学文摘社编号:
33386-08-2
分子量:
421.96
NACRES:
NA.77
PubChem Substance ID:
24278079
UNSPSC Code:
12352200
EC Number:
251-489-4
MDL number:
MFCD00078569
Form:
powder
Quality level:
100
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产品名称

丁螺环酮盐酸盐 盐酸盐,

form

powder

Quality Level

100

originator

Bristol-Myers Squibb

storage temp.

2-8°C

SMILES string

Cl[H].O=C1CC2(CCCC2)CC(=O)N1CCCCN3CCN(CC3)c4ncccn4

InChI

1S/C21H31N5O2.ClH/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20;/h5,8-9H,1-4,6-7,10-17H2;1H

InChI key

RICLFGYGYQXUFH-UHFFFAOYSA-N

Gene Information

human ... HTR1A(3350)

Biochem/physiol Actions

5-HT 1A 血清素受体激动剂；抗焦虑药。

Features and Benefits

该化合物由Bristol-Myers Squibb开发。要浏览其他药物开发化合物和批准的药物/候选药物列表，单击此处。
这种化合物是神经科学研究的特色产品。 点击此处 ，发现更多特色神经科学产品。访问sigma.com/discover-bsm了解更多关于其他研究领域的生物活性小分子的信息。

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCK4551
BCCG0755
BCCC9648
BCBZ3793
BCBW1483

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DISCOVER Bioactive Small Molecules for Neuroscience

DISCOVER Bioactive Small Molecules for Neuroscience

相关内容

Product Information Sheet - B7148

Product Information Sheet

E Meller et al.
Molecular pharmacology, 37(2), 231-237 (1990-02-01)
The irreversible receptor antagonist N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) was used to determine the relationship between receptor occupancy and response at central 5-hydroxytryptamine1A (5-HT1A) serotonin receptors mediating the inhibition of serotonin synthesis in rat cortex and hippocampus. Rats were treated with vehicle or
G Tunnicliff
Pharmacology & toxicology, 69(3), 149-156 (1991-09-01)
Buspirone has been available in the United States for over four years for the treatment of anxiety. It was anticipated this drug would offer certain advantages over the established benzodiazepines. In contrast to diazepam, early studies found no evidence for
Repurposing buspirone for drug addiction treatment.
Bernard Le Foll et al.
The international journal of neuropsychopharmacology, 16(2), 251-253 (2012-11-24)
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全球贸易项目编号

货号GTIN
B7148-5G04061833441558
B7148-1G04061833441541