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Merck
CN

A8980

阿卡波糖

≥95% (HPLC)

别名:

4",6"-二脱氧-4"-([1S]-[1,4,6/5]-4,5,6-三羟基-3-羟甲基-2-环己烯基氨基)-麦芽三糖

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关于此项目

经验公式(希尔记法):
C25H43NO18
化学文摘社编号:
分子量:
645.60
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
EC Number:
260-030-7
MDL number:
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产品名称

阿卡波糖, ≥95% (HPLC)

InChI

1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1

InChI key

XUFXOAAUWZOOIT-SXARVLRPSA-N

SMILES string

C[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O[C@@H]2CO)O[C@H]3[C@H](O)[C@@H](O)[C@H](O)O[C@@H]3CO)[C@H](O)[C@@H](O)[C@@H]1N[C@H]4C=C(CO)[C@@H](O)[C@H](O)[C@H]4O

biological source

bacterial (Actinoplanes)

assay

≥95% (HPLC)

form

powder

impurities

<9.4% water (Karl Fischer)

color

white to off-white

solubility

H2O (CO2 free): 50 mg/mL, clear, colorless

storage temp.

room temp

Quality Level

Gene Information

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Application

阿卡波糖是一种衍生的麦芽三糖抗糖尿病药,是一种可逆的α-葡萄糖苷酶抑制剂,用于医学研究以控制II型糖尿病的作用。阿卡波糖通常被用作比较其他α-葡萄糖苷酶抑制剂的参考。

Biochem/physiol Actions

作为可逆性α-葡萄糖苷酶抑制剂的改性四糖。

Other Notes

为了全面了解我们针对客户研究提供的各种寡糖产品,建议您访问我们的碳水化合物分类页面。

存储类别

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Muhammad Jihad Sandikapura et al.
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The study was aimed to perform aqueous extraction of two plants using different extraction methods, and evaluate their antioxidant and antidiabetic potential. Plant materials were extracted by maceration, soxhlet, sonication and fresh juice methods to produce aqueous extracts. In vitro
Ranee Singh et al.
Journal of feline medicine and surgery, 17(10), 848-857 (2014-10-26)
Feeding a low carbohydrate diet is recommended for diabetic cats; however, some cats may require diets containing moderate-to-high carbohydrate and may benefit from the use of therapeutic agents to improve glycemic control. The aim of the study was to determine
Alessandro Leone et al.
Nutrients, 10(10) (2018-10-17)
The hypoglycemic effect in humans of Moringa oleifera (MO) leaf powder has, to date, been poorly investigated. We assessed the chemical composition of MO leaf powder produced at Saharawi refugee camps, its in vitro ability to inhibit α-amylase activity, and
Ashley S Boath et al.
Food chemistry, 135(3), 929-936 (2012-09-08)
Polyphenol-rich extracts from certain berries inhibited α-glucosidase activity in vitro. The two most effective berry extracts, from black currant and rowanberry, inhibited α-glucosidase with IC(50) values respectively of 20 and 30μg GAE/ml and were as effective as the pharmaceutical inhibitor
Henriëtte J Rozeboom et al.
The Journal of biological chemistry, 288(37), 26764-26774 (2013-08-02)
α-1,4-Glucan lyase (EC 4.2.2.13) from the red seaweed Gracilariopsis lemaneiformis cleaves α-1,4-glucosidic linkages in glycogen, starch, and malto-oligosaccharides, yielding the keto-monosaccharide 1,5-anhydro-D-fructose. The enzyme belongs to glycoside hydrolase family 31 (GH31) but degrades starch via an elimination reaction instead of

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