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安全信息

A7736

Sigma-Aldrich

白蛋白 人

recombinant, expressed in Pichia pastoris, lyophilized powder, ≥90% (agarose gel electrophoresis)

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别名:
Albagen, rHSA
经验公式(希尔记法):
C2936H4624N786O889S41
CAS号:
分子量:
66471.53
EC 号:
MDL编号:
UNSPSC代码:
12352202
NACRES:
NA.25

生物来源

human

质量水平

重组

expressed in Pichia pastoris

检测方案

≥90% (agarose gel electrophoresis)

形式

lyophilized powder

分子量

monomer ~67 kDa

技术

cell culture | mammalian: suitable

UniProt登记号

储存温度

2-8°C

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

InChI key

QYSGYZVSCZSLHT-UHFFFAOYSA-N

基因信息

human ... ALB(213)

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应用

该重组变异建议用于:吸收、分散、代谢和排泄(ADME)药理学研究;细胞培养;药物递送研究;细胞冻存。

生化/生理作用

白蛋白是可见于动物体液和组织及部分植物种子的一类可溶性单体蛋白。 血清白蛋白可作为类固醇、脂肪酸和甲状腺激素的载体蛋白。 血清白蛋白在调节血液的胶体渗透压方面也至关重要。

物理属性

从N端删除单个Asp可产生低过敏性构建体。X射线晶体学证实了其与天然白蛋白的结构等同性。Asp缺失通过消除白蛋白主要的铜镍结合位点而去除了重要的抗原决定簇。人白蛋白的前三个残基被认为是非结构性的。还在Cys34上进行阻断,以改善稳定性、单体含量和均一性。

其他说明

更多信息参见人血清白蛋白

法律信息

Albagen is a trademark of Albumin Therapeutics, LLC.

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品

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