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Merck
CN

A5626

氯化乙酰硫代胆碱

≥99% (TLC), powder

别名:

(2-Mercaptoethyl)trimethylammonium chloride acetate

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关于此项目

线性分子式:
CH3COSCH2CH2N(CH3)3Cl
化学文摘社编号:
分子量:
197.73
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
227-953-7
MDL number:
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InChI key

GZYVLKKMMDFCKR-UHFFFAOYSA-M

InChI

1S/C7H16NOS.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

SMILES string

[Cl-].CC(=O)SCC[N+](C)(C)C

assay

≥99% (TLC)

form

powder

solubility

water: 100 mg/mL, clear to slightly hazy, colorless

storage temp.

−20°C

Quality Level

Gene Information

human ... ACHE(43)

Application

氯化乙酰胆碱用于确定精液外泌体(SE)中乙酰胆碱酯酶的活性。也可用作乙酰胆碱酯酶的底物,对其动力学参数进行微量量热研究。

Biochem/physiol Actions

乙酰胆碱酯酶底物和烟碱型乙酰胆碱受体激动剂。
乙酰胆碱酯酶(AChE)酶在神经传递过程中起着重要的生理作用。

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tanja Botić et al.
European journal of medicinal chemistry, 136, 294-304 (2017-05-16)
The brominated pyrroloiminoquinone alkaloids discorhabdins B, L and G and 3-dihydro-7,8- dehydrodiscorhabdin C, isolated from methanol extracts of two specimens of Latrunculia sp. sponges collected near the Antarctic Peninsula, are here demonstrated for the first time to be reversible competitive
Isolation of Exosomes from Semen for in vitro Uptake and HIV-1 Infection Assays
Madison MN, et al.
Bio-protocol, 7(7) (2017)
Livia F Sgobbi et al.
Biosensors & bioelectronics, 100, 290-297 (2017-09-25)
A plethora of publications has continuously reported electrochemical biosensors for detection of pesticides. However, those devices rarely accomplish commercial application due to technical issues associated with the lack of stability and high cost of the biological recognition element (enzyme). Alternatively
Muhammad Shakil Shah et al.
Computational biology and chemistry, 76, 310-317 (2018-08-25)
Cholinesterases (ChEs) play a vital role in regulating cholinergic transmission. Inhibition of ChEs is thought to be an emerging and useful therapeutic target for neurodegenerative disorders through restoration of acetylcholine (ACh) levels in the brain (e.g. Alzheimer's disease). To increase
Dandan Song et al.
Analytica chimica acta, 982, 168-175 (2017-07-25)
A highly sensitive acetylcholinesterase (AChE) electrochemical biosensor for the quantitative determination of organophosphate pesticides (OPs) in vegetables and fruits based on palladium-copper nanowires (Pd-Cu NWs) was reported. AChE immobilized on the modified electrode could catalyze hydrolysis of acetylthiocholine chloride (ATCl)

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