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Merck
CN

A2661

Sigma-Aldrich

氯化乙酰胆碱

suitable for cell culture

别名:

ACh

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About This Item

线性分子式:
(CH3)3N+CH2CH2OCOCH3Cl-
CAS号:
分子量:
181.66
Beilstein:
3571875
EC 号:
MDL编号:
UNSPSC代码:
12352209
eCl@ss:
32190102
PubChem化学物质编号:
NACRES:
NA.75

生物来源

synthetic

质量水平

检测方案

~99%

形式

powder

技术

cell culture | mammalian: suitable

mp

146-150 °C (lit.)

溶解性

water: 100 mg/mL, clear, colorless

运输

ambient

储存温度

room temp

SMILES字符串

[Cl-].CC(=O)OCC[N+](C)(C)C

InChI

1S/C7H16NO2.ClH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

JUGOREOARAHOCO-UHFFFAOYSA-M

基因信息

human ... CHRM3(1131)

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应用

氯化乙酰胆碱已用于制备乙酰胆碱,是乙酰胆碱(ACh)离子导入的常用溶媒。它还用于处理aNS-1来源神经元以进行cAMP(环腺苷单磷酸)分析,也用于检测其对G蛋白偶联受体(GPCR)的影响作用。

生化/生理作用

氯化乙酰胆碱,20mg/kg体重注射,减少小鼠实验性诱发脓毒病的死亡和血浆促炎细胞因子。类胆碱能抗-炎症机制可能通过乙酰胆碱和 α7n单核细胞,巨噬细胞和中性粒细胞上的胆红素受体互作接待,降低了促炎细胞活素,比如 TNF-α,IL-1β,和IL-6。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


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The erythropoietin-producing human hepatocellular receptor EPH receptor B6 (EPHB6) is a receptor tyrosine kinase that has been shown previously to control catecholamine synthesis in the adrenal gland chromaffin cells (AGCCs) in a testosterone-dependent fashion. EPHB6 also has a role in
M Omar Al-Zi'abi et al.
Biology of reproduction, 80(4), 823-832 (2009-01-09)
The present study was conducted to explore the source of acetylcholine (ACH) in the corpus luteum (CL) and to test our hypothesis of an antiapoptotic role of ACH in the bovine CL and, further, to investigate whether nerve growth factor

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