生物来源
synthetic
质量水平
检测方案
≥99% (titration)
形式
powder
技术
cell culture | mammalian: suitable
颜色
white
mp
207-209 °C (dec.) (lit.)
溶解性
H2O: 50 mg/mL
SMILES字符串
NCCCCCC(O)=O
InChI
1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
InChI key
SLXKOJJOQWFEFD-UHFFFAOYSA-N
基因信息
human ... PLAT(5327) , PLG(5340)
rat ... Ppm1a(24666)
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相关类别
应用
EAC以25mg/ml溶解于水。因为是纤溶酶抑制剂，它被用在纤维蛋白酶分析凝血缓冲液。缓冲液是10mM磷酸钾和磷酸钠，pH6.4，再加上0.20gCaCl2, 5g 6-氨基己酸，1g叠氮化钠和9g氯化钠，都溶解在1升体系里。缓冲液在室外下无限期稳定。
生化/生理作用
EACA被报道能够抑制糜蛋白酶、因子VIIA、赖氨酸碳氧基肽酶、纤溶酶，纤溶酶原激活物。
赖氨酸类似物。促进纤溶酶的快速解离，从而抑制纤溶酶原的活化和随后的纤维蛋白溶解。据报道可抑制纤溶酶原与活化的血小板结合。 早期报告表明，它抑制补体系统第一成分的激活。结合羧肽酶 B并使其灭活。
WGK
WGK 2
闪点(°F)
404.6 - 408.2 °F
闪点(°C)
207 - 209 °C
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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Analytical Enzyme Chymotrypsin: Chymotrypsin is produced in the acinar cells of the pancreas as the inactive precursor, chymotrypsinogen.
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