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A2504

6-氨基己酸

Name: 6-氨基己酸
Brand: SIGMA

≥99% (titration), powder

别名:

ε-氨基己酸, 6-氨基己酸, EACA

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关于此项目

线性分子式:

H₂N(CH₂)₅CO₂H

化学文摘社编号:

60-32-2

分子量:

131.17

UNSPSC Code:

12352202

NACRES:

NA.77

PubChem Substance ID:

24890662

EC Number:

200-469-3

Beilstein/REAXYS Number:

906872

MDL number:

MFCD00008238

Assay:

≥99% (titration)

Form:

powder

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属性

biological source

synthetic

Quality Level

300

assay

≥99% (titration)

form

powder

technique(s)

cell culture | mammalian: suitable

color

white

mp

207-209 °C (dec.) (lit.)

solubility

H₂O: 50 mg/mL

SMILES string

NCCCCCC(O)=O

InChI

1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)

InChI key

SLXKOJJOQWFEFD-UHFFFAOYSA-N

Gene Information

human ... PLAT(5327), PLG(5340)
rat ... Ppm1a(24666)

说明

Application

EAC以25mg/ml溶解于水。因为是纤溶酶抑制剂，它被用在纤维蛋白酶分析凝血缓冲液。缓冲液是10mM磷酸钾和磷酸钠，pH6.4，再加上0.20gCaCl₂, 5g 6-氨基己酸，1g叠氮化钠和9g氯化钠，都溶解在1升体系里。缓冲液在室外下无限期稳定。

Biochem/physiol Actions

EACA被报道能够抑制糜蛋白酶、因子VIIA、赖氨酸碳氧基肽酶、纤溶酶，纤溶酶原激活物。

赖氨酸类似物。促进纤溶酶的快速解离，从而抑制纤溶酶原的活化和随后的纤维蛋白溶解。

赖氨酸类似物。促进纤溶酶的快速解离，从而抑制纤溶酶原的活化和随后的纤维蛋白溶解。据报道可抑制纤溶酶原与活化的血小板结合。早期报告表明，它抑制补体系统第一成分的激活。结合羧肽酶 B并使其灭活。

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存储类别

11 - Combustible Solids

flash_point_f

404.6 - 408.2 °F

flash_point_c

207 - 209 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

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