形式
powder
质量水平
旋光性
[α]23/D −10.5°, c = 0.5 in H2O(lit.)
颜色
white to beige
mp
148-152 °C (lit.)
溶解性
0.1 M HCl: soluble
SMILES字符串
CC(C)NC[C@H](O)COc1ccc(CC(N)=O)cc1
InChI
1S/C14H22N2O3/c1-10(2)16-8-12(17)9-19-13-5-3-11(4-6-13)7-14(15)18/h3-6,10,12,16-17H,7-9H2,1-2H3,(H2,15,18)/t12-/m0/s1
InChI key
METKIMKYRPQLGS-LBPRGKRZSA-N
基因信息
human ... ADRB1(153)
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应用
(S)-(-)-Atenolol may be used as a standard in the preparation of enantiomer for high-performance liquid chromatography-tandem mass spectrometry studies (HPLC-MS/MS). It has also been used in the β blocking molecule for Raman spectroscopy studies.
生化/生理作用
(S)-(-)-Atenolol is a β1-adrenergic receptor antagonist and an active enantiomer of atenolol.
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
The influence of molecular structure modifications on vibrational properties of some beta blockers: a combined raman and DFT study
Farca? A, et al.
Journal of Spectroscopy (New York, NY, United States) (2016)
Kevin F Morris et al.
Chemical physics, 457, 133-146 (2015-08-11)
Molecular dynamics simulations and NMR spectroscopy were used to compare the binding of two β-blocker drugs to the chiral molecular micelle poly-(sodium undecyl-(L)-leucine-valine). The molecular micelle is used as a chiral selector in capillary electrophoresis. This study is part of
A A Pearson et al.
The Journal of pharmacology and experimental therapeutics, 250(3), 759-763 (1989-09-01)
Previous studies have demonstrated that propranolol can lower arterial pressure through an action within the central nervous system. The purpose of this study was to determine 1) whether the hydrophilic beta blocking drug atenolol which is devoid of membrane stabilizing
S A Doggrell
Chirality, 5(1), 8-14 (1993-01-01)
The effects of (+/-)-, (+)-, and (-)-atenolol, sotalol, and amosulalol alone on the rat left atria and portal vein and on the respective beta 1- and beta 2-adrenoceptor-mediated responses to isoprenaline have been determined. (+/-)-Atenolol at 10(-6) M had no
Ulisse Garbin et al.
Mediators of inflammation, 2008, 367590-367590 (2008-04-26)
The endothelium plays a key role in the development of atherogenesis and its inflammatory and proliferative status influences the progression of atherosclerosis. The aim of this study is to compare the effects of two beta blockers such as nebivolol and
Chromatograms
application for HPLC我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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