A1086

N-乙酰基-Asp-Glu-Val-Asp-7-酰胺基-4-甲基香豆素

Name: N-乙酰基-Asp-Glu-Val-Asp-7-酰胺基-4-甲基香豆素
Brand: SIGMA

≥97% (HPLC), Fluorogenic caspase 3 substrate, powder

别名:

Ac-DEVD-AMC

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关于此项目

经验公式（希尔记法）:

C₃₀H₃₇N₅O₁₃

化学文摘社编号:

169332-61-0

分子量:

675.64

UNSPSC Code:

12352209

PubChem Substance ID:

24890505

NACRES:

NA.77

MDL number:

MFCD00671411

主要文件

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产品名称

N-乙酰基-Asp-Glu-Val-Asp-7-酰胺基-4-甲基香豆素, ≥97% (HPLC), powder

SMILES string

CC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2C(C)=CC(=O)Oc2c1

InChI

1S/C30H37N5O13/c1-13(2)26(35-27(44)18(7-8-22(37)38)33-29(46)19(11-23(39)40)31-15(4)36)30(47)34-20(12-24(41)42)28(45)32-16-5-6-17-14(3)9-25(43)48-21(17)10-16/h5-6,9-10,13,18-20,26H,7-8,11-12H2,1-4H3,(H,31,36)(H,32,45)(H,33,46)(H,34,47)(H,35,44)(H,37,38)(H,39,40)(H,41,42)/t18-,19-,20-,26-/m0/s1

InChI key

ALZSTTDFHZHSCA-RNVDEAKXSA-N

assay

≥97% (HPLC)

form

powder

composition

Peptide content, ~65%

color

white

solubility

DMSO: 10 mM

storage temp.

−20°C

Quality Level

100

Application

N-乙酰基-Asp-Glu-Val-Asp-7-酰胺基-4-甲基香豆素已被用作人结肠癌细胞系和骨髓间充质干细胞中caspase-3检测的底物。

Biochem/physiol Actions

caspase 3的荧光底物，而caspase 3是一种当细胞暴露于凋亡条件下时会被快速激活并裂解聚（ADP-核糖）聚合酶的蛋白酶。

Features and Benefits

该化合物在受体分类和信号转导手册的半胱天冬酶页面上有详细描述。如需浏览其他手册页面，请点击此处。

这种化合物是细胞凋亡研究的特色产品。点击此处发现更多特色细胞凋亡产品。在sigma.com/discover-bsm可了解更多关于生物活性小分子的其他研究领域。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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N-乙酰基-Asp-Glu-Val-Asp-7-酰胺基-4-甲基香豆素

≥97% (HPLC), Fluorogenic caspase 3 substrate, powder

选择尺寸

关于此项目

主要文件

属性

产品名称

SMILES string

InChI

InChI key

assay

form

composition

color

solubility

storage temp.

Quality Level

相关类别

说明

Application

Biochem/physiol Actions

Features and Benefits

安全信息

存储类别

wgk

flash_point_f

flash_point_c

ppe

法规信息

文件

分析证书(COA)

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