跳转至内容
Merck
CN

A0673

Sigma-Aldrich

人肾上腺皮质激素片段 18-39

≥97% (HPLC)

别名:

CLIP

登录查看公司和协议定价


About This Item

经验公式(希尔记法):
C112H165N27O36
CAS号:
分子量:
2465.67
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.32
表单:
powder
方案:
≥97% (HPLC)

无菌性

non-sterile

质量水平

方案

≥97% (HPLC)

表单

powder

UniProt登记号

储存温度

−20°C

SMILES字符串

CC(C)CC(NC(=O)C1CCCN1C(=O)C(Cc2ccccc2)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C)NC(=O)C(CO)NC(=O)C(CCC(O)=O)NC(=O)C(CC(O)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C)NC(=O)CNC(=O)C(CC(N)=O)NC(=O)C3CCCN3C(=O)C(Cc4ccc(O)cc4)NC(=O)C(NC(=O)C(CCCCN)NC(=O)C(NC(=O)C5CCCN5C(=O)C(N)CCCNC(N)=N)C(C)C)C(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(Cc6ccccc6)C(O)=O

InChI

1S/C112H165N27O36/c1-56(2)48-72(100(163)125-70(37-41-86(148)149)97(160)133-77(111(174)175)51-63-24-14-11-15-25-63)129-103(166)79-28-20-46-138(79)109(172)75(49-62-22-12-10-13-23-62)131-93(156)61(9)121-95(158)68(35-39-84(144)145)123-92(155)60(8)122-102(165)78(55-140)134-98(161)71(38-42-87(150)151)126-101(164)74(53-88(152)153)128-96(159)69(36-40-85(146)147)124-91(154)59(7)120-83(143)54-119-94(157)73(52-82(115)142)130-104(167)80-29-21-47-139(80)110(173)76(50-64-31-33-65(141)34-32-64)132-107(170)89(57(3)4)135-99(162)67(27-16-17-43-113)127-106(169)90(58(5)6)136-105(168)81-30-19-45-137(81)108(171)66(114)26-18-44-118-112(116)117/h10-15,22-25,31-34,56-61,66-81,89-90,140-141H,16-21,26-30,35-55,113-114H2,1-9H3,(H2,115,142)(H,119,157)(H,120,143)(H,121,158)(H,122,165)(H,123,155)(H,124,154)(H,125,163)(H,126,164)(H,127,169)(H,128,159)(H,129,166)(H,130,167)(H,131,156)(H,132,170)(H,133,160)(H,134,161)(H,135,162)(H,136,168)(H,144,145)(H,146,147)(H,148,149)(H,150,151)(H,152,153)(H,174,175)(H4,116,117,118)

InChI key

ZYDMZKPAPSZILB-UHFFFAOYSA-N

基因信息

human ... POMC(5443)

正在寻找类似产品? 访问 产品对比指南

Amino Acid Sequence

Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe

一般描述

促肾上腺皮质激素 (ACTH) 由其前体阿黑皮素原 (POMC) 合成。在下丘脑促肾上腺皮质激素释放激素 (CRH) 的作用下,由垂体前叶释放。ACTH 的编码基因定位于人染色体 2p23.3。

应用

促肾上腺皮质激素片段 18-39 人已用于基质辅助激光解吸/离子化 (MALDI)-TOF-MS 和 MALDI-MS。

生化/生理作用

促肾上腺皮质激素(ACTH)通过cAMP依赖于肾上腺中G蛋白偶联受体的刺激来刺激糖皮质激素和雄激素的合成和释放。ACTH的过量生产会导致皮肤色素沉着。
对大鼠异相睡眠的促进作用:刺激胰岛素释放。

其他说明

通过 H 2 O 中的 0.1% TFA冻干

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Long time storage (archiving) of peptide, protein and tryptic digest samples on disposable nano-coated polymer targets for MALDI MS
Stefan B, et al.
Annals of the Rheumatic Diseases, 8, 48-54 (2015)
Reinhild Kappelhoff et al.
Biochimica et biophysica acta, 1864(11 Pt B), 2210-2219 (2017-08-12)
The protease degradome is defined as the complete repertoire of proteases and inhibitors, and their nonfunctional homologs present in a cell, tissue or organism at any given time. We review the tissue distribution of virtually the entire degradome in 23
Sumedha Sharma et al.
BMC health services research, 17(1), 238-238 (2017-03-30)
Despite increased investment in community-level maternal health interventions, process evaluations of such interventions are uncommon, and can be instrumental in understanding mediating factors leading to outcomes. In Nigeria, where an unacceptably number of maternal deaths occur (maternal mortality ratio of
Endocrinology (2001)
Patrick A Ott et al.
Nature, 547(7662), 217-221 (2017-07-06)
Effective anti-tumour immunity in humans has been associated with the presence of T cells directed at cancer neoantigens, a class of HLA-bound peptides that arise from tumour-specific mutations. They are highly immunogenic because they are not present in normal tissues

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门