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安全信息

L7386

Sigma-Aldrich

溶葡球菌酶 来源于溶葡萄球菌

≥500 units/mg protein, lyophilized powder

别名:

甘氨酰-甘氨酸内肽酶

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About This Item

CAS号:
9011-93-2
EC 号:
3.4.24.75 (BRENDA, IUBMB)
MDL编号:
MFCD00131556
UNSPSC代码:
12352204
NACRES:
NA.54

product name

溶葡球菌酶 来源于溶葡萄球菌, lyophilized powder, Protein 50-70 % by biuret, ≥500 units/mg protein

生物来源

microbial (Staphylococcus staphylotyticus)

质量水平

300

形式

lyophilized powder

比活

≥500 units/mg protein

分子量

25 kDa

组成

Protein, 50-70% biuret

包装

pkg of (sold on basis of mg protein)

溶解性

water: 2.00-2.10 mg/mL, clear to slightly hazy, colorless to light yellow

抗生素抗菌谱

Gram-positive bacteria

应用

diagnostic assay manufacturing
diagnostic assay manufacturing

作用机制

cell wall synthesis | interferes

运输

wet ice

储存温度

−20°C

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一般描述

化学结构：多肽

生化/生理作用

溶葡萄球菌素是一种分子量约为25 kDa的锌内肽酶。 由于溶葡萄球菌酶能裂解 葡萄球菌 类细胞壁肽聚糖层中的聚甘氨酸交联键，它已被发现可用于细胞裂解，并具有潜在的抗菌治疗作用。
活性最佳pH：约 7.5

单位定义

一个单位在25°C和pH 7.5条件下，在6.0 m反应混合物中可使 金黄色酿脓葡萄球菌 细胞悬浮液的浊度（A620）在10分钟内由0.250降至0.125。

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H334

危险分类

Resp. Sens. 1

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

常规特殊物品

分析证书(COA)

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Ian R Monk et al.
Nature communications, 10(1), 3067-3067 (2019-07-13)
WalKR (YycFG) is the only essential two-component regulator in the human pathogen Staphylococcus aureus. WalKR regulates peptidoglycan synthesis, but this function alone does not explain its essentiality. Here, to further understand WalKR function, we investigate a suppressor mutant that arose
Catherine Bennett et al.
International forum of allergy & rhinology, 9(8), 918-925 (2019-06-05)
Chronic rhinosinusitis (CRS) is a common disease, often refractory to conventional antimicrobial treatment. In this study we investigate the antimicrobial and anti-inflammatory effects of adding kappa-carrageenan to a commercially available sinus rinse. Kappa-carrageenan was added to Flo CRS and Flo
Dafne Bongiorno et al.
MicrobiologyOpen, 9(5), e1017-e1017 (2020-04-03)
Methicillin-resistant S. aureus has been reported as the main pathogen involved in chronic infections, osteomyelitis, and prosthetic joint infections. The host/pathogen interaction is dynamic and requires several changes to promote bacterial survival. Here, we focused on the internalization and persistence
Judy J J Ou et al.
Frontiers in cellular and infection microbiology, 6, 187-187 (2017-01-14)
Background:Staphylococcus aureus (S. aureus) small colony variants (SCVs) can survive within the host intracellular milieu and are associated with chronic relapsing infections. However, it is unknown whether host invasion rates and immune responses differ between SCVs and their wild-type counterparts.
Igor Belyansky et al.
The Journal of surgical research, 171(2), 409-415 (2011-06-24)
Lysostaphin (LS), a naturally occurring Staphylococcal endopeptidase, has the ability to penetrate biofilm, and has been identified as a potential antimicrobial to prevent mesh infection. The goals of this study were to determine if LS adhered to porcine mesh (PM)
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实验方案

GenElute™ Bacterial Genomic DNA Kit Protocol (NA2100, NA2110, NA2120)

GenElute™ Bacterial Genomic DNA Kit protocol describes a simple and convenient way for the isolation of pure genomic DNA from bacteria.

GenElute™细菌基因组DNA试剂盒实验方案（NA2100、NA2110、NA2120）

的GenElute™细菌基因组DNA试剂盒提供了一种从细菌中分离纯基因组DNA的简便方法。

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