推荐产品
一般描述
纤维蛋白通过纤维蛋白原的凝血酶交联产生。纤维蛋白原由两个单体组成，每个单体含有三条多肽链。纤维蛋白原是一种主要的血浆蛋白。
应用
来自人血浆中的纤维蛋白已用于：
- 纤维蛋白原和纤维蛋白的体外切割
- 作为拉曼光谱真成分分析（TCA）和主成分分析（PCA）的参考
- 作为拉曼光谱的参考，以研究不同多金属氧酸盐（POM）的结合机理和结合效率。
生化/生理作用
纤维蛋白是初级凝血过程中的重要生物聚合物。它为组织修复过程中浸润细胞提供了支架。纤维蛋白被广泛用作组织再生应用的组织密封剂，因为它能够形成生物相容性的物理结构。它也被用于细胞和生物活性分子的输送系统。纤维蛋白基质类似于天然胰腺，可作为胰岛移植的支架材料。纤维蛋白已在研究中用于获得纤维蛋白特异性单克隆抗体（mAb）。这些mAb可用于确定它们在纤维蛋白聚合中的作用以及在血浆中纤维蛋白定量中的用途。
制备说明
通过凝固纤维蛋白原制备以产生交联纤维蛋白
免责声明
供研究使用在法国，在用于科研目的时（包括进口和出口活动（《公共健康法》第L 1211-1条，第2节））该产品为管制品。购买者（即最终用户）需要获得《公共健康法》法第L 1211-1条规定的法国研究部的进口授权。订购本产品即表明您确认已经获得合适的进口授权。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Matthew Riopel et al.
Acta biomaterialia, 9(9), 8140-8148 (2013-06-12)
Extracellular matrix (ECM)-integrin stimulation can promote beta cell differentiation, proliferation and function. However, beta cells lose their insulin secretion function in response to glucose stimulation, and senesce when cultured with ECM proteins for a long time. Fibrin is a provisional
Kohji Kasahara et al.
Blood, 122(19), 3340-3348 (2013-09-05)
Membrane rafts are spatially and functionally heterogenous in the cell membrane. We observed that lysenin-positive sphingomyelin (SM)-rich rafts are identified histochemically in the central region of adhered platelets where fibrin and myosin are colocalized on activation by thrombin. The clot
B J De Kort et al.
Acta biomaterialia, 135, 243-259 (2021-09-13)
In situ heart valve tissue engineering is an emerging approach in which resorbable, off-the-shelf available scaffolds are used to induce endogenous heart valve restoration. Such scaffolds are designed to recruit endogenous cells in vivo, which subsequently resorb polymer and produce
Abraham R Alfonso et al.
Acta biomaterialia, 9(9), 8149-8157 (2013-06-26)
Tissue engineered heart valves (TEHVs) may provide a permanent solution to congenital heart valve disease by permitting somatic valve growth in the pediatric patient. However, to date, TEHV studies have focused primarily on collagen, the dominant component of valve extracellular
Kristen T Morin et al.
Experimental cell research, 319(16), 2409-2417 (2013-06-27)
In vitro models of endothelial assembly into microvessels are useful for the study of angiogenesis and vasculogenesis. In addition, such models may be used to provide the microvasculature required to sustain engineered tissues. A large range of in vitro models
商品
Cell based angiogenesis assays to analyze new blood vessel formation for applications of cancer research, tissue regeneration and vascular biology.
在癌症研究、组织再生和血管生物学应用中通过以细胞为基础的血管生成检测来分析新血管的形成。
Highlighting existing and novel fabrication methods for both, solid and hydrogel-based scaffold for tissue engineering applications.
将基于水凝胶的生物材料用于递送和募集细胞以促进体内组织再生是新生的研究热题。本文讨论了水凝胶在细胞递送和组织再生中的应用。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门