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胃蛋白酶来源于猪胃粘膜

Name: 胃蛋白酶 来源于猪胃粘膜
Brand: SIGMA
Price: 631.4 CNY
Availability: InStock

powder, slightly beige, 1200-2400 U/mg

别名:

胃液素来源于猪胃, 胃蛋白酶 A

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500 G

¥631.40

1 KG

¥663.75

¥631.40

预计发货时间2025年5月23日详情

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500 G

¥631.40

1 KG

¥663.75

About This Item

CAS号:

9001-75-6

EC 号:

3.4.23.1 (BRENDA, IUBMB)

EC 号:

232-629-3

MDL编号:

MFCD00081840

UNSPSC代码:

12352204

eCl@ss:

42010127

NACRES:

NA.54

¥631.40

预计发货时间2025年5月23日详情

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此商品	P5739	T5694	SRP3236
T4184 Thrombopoietin from mouse	P5739 Placenta Growth Factor-2 from mouse	T5694 TRAIL human	SRP3236 TPO from mouse
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable
assay >97% (SDS-PAGE)	assay >97% (SDS-PAGE)	assay >97% (SDS-PAGE)	assay ≥98% (HPLC), ≥98% (SDS-PAGE)
recombinant expressed in NSO cells	recombinant expressed in baculovirus infected Sf21 cells	recombinant expressed in NSO cells	recombinant expressed in E. coli
form lyophilized powder	form lyophilized powder	form lyophilized powder	form lyophilized
mol wt ~75 kDa by SDS-PAGE (as a result of glycosylation), predicted mol wt 35 kDa	mol wt ~38 kDa by SDS-PAGE	mol wt 24 kDa by SDS-PAGE, predicted mol wt ~21 kDa	mol wt 18.7 kDa

应用

胃蛋白酶切割可用于产生抗体的F(ab′)₂ 片段。有关胃蛋白酶的更多信息，请访问 www.sigma-aldrich.com/enzymeexplorer。

生化/生理作用

优先裂解：P1 和 P1′ 位的疏水性和芳族残基。降解胰岛素 β 链中的 Phe-Val、Gln-His、Glu-Ala、Ala-Leu、Leu-Tyr、Tyr-Leu、Gly-Phe、Phe-Phe 和 Phe-Tyr 键

单位定义

在pH 2.0和37℃条件下，1 U对应于每分钟使280 nm处的吸光度增加0.001的酶量（血红蛋白，货号51290，作为底物）如上所述的15′000吸光度-U相当于 ∼1 Bergmeyer-U。 1 Bergmeyer-U是在pH 2.0和37℃条件下水解1 μmmol乙酰基-L-苯基-3,5-二碘代-L-酪氨酸的酶量

分析说明

最适pH值为2-4。在4 M尿素和3 M盐酸胍中可保持活性。在60°C时稳定。胃蛋白酶在pH 8.0-8.5下发生不可逆灭活。

免责声明

Sales restrictions may apply.

象形图

GHS08,GHS07

警示用语：

Danger

危险声明

H315,H319,H334,H335

预防措施声明

P261 - P264 - P271 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338

危险分类

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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动植物源性产品

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Fourier Transform Infrared Spectroscopy for Assessing Structural and Enzymatic Reactivity Changes Induced during Feather Hydrolysis.

Xinhua Windt et al.

ACS omega, 7(44), 39924-39930 (2022-11-18)

Chicken feathers are major byproducts of the livestock processing industry with high potential in the feed sector. In this study, we present a new approach using Fourier transform infrared (FTIR) spectroscopy to detect the structural changes of feather keratin and

Structural changes and allergenic properties of β-lactoglobulin upon exposure to high-intensity ultrasound.

Dragana Stanic-Vucinic et al.

Molecular nutrition & food research, 56(12), 1894-1905 (2012-10-16)

The aim of this work was to investigate the effects of high-intensity ultrasound (sonication), on the structure and allergenicity of the major cow's milk allergen, beta-lactoglobulin (BLG). Structural changes upon sonication of BLG were monitored by circular dichroism spectroscopy, tryptophan

Gastric proteinases--structure, function, evolution and mechanism of action.

B Foltmann

Essays in biochemistry, 17, 52-84 (1981-01-01)

High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis.

Benoît Stijlemans et al.

PLoS pathogens, 7(6), e1002072-e1002072 (2011-06-24)

The African trypanosome Trypanosoma brucei, which persists within the bloodstream of the mammalian host, has evolved potent mechanisms for immune evasion. Specifically, antigenic variation of the variant-specific surface glycoprotein (VSG) and a highly active endocytosis and recycling of the surface

Review article: role of pepsin and bile in gastro-oesophageal reflux disease.

J Tack

Alimentary pharmacology & therapeutics, 22 Suppl 1, 48-54 (2005-07-27)

Gastro-oesophageal reflux disease is defined as the presence of symptoms or lesions that can be attributed to the reflux of gastric contents into the oesophagus. Aspiration and prolonged monitoring studies in humans have shown that reflux of gastric contents is

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胃蛋白酶 来源于猪胃粘膜

powder, slightly beige, 1200-2400 U/mg

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WGK

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胃蛋白酶来源于猪胃粘膜