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Merck
CN
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文件

70050

Sigma-Aldrich

杨梅黄素

≥96.0% (HPLC)

别名:

3,3′,4′,5,5′,7-六羟基黄酮, 大麻双酮, 杨梅醇

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About This Item

经验公式（希尔记法）:
C15H10O8
CAS号:
529-44-2
分子量:
318.24
Beilstein:
332331
EC 号:
208-463-2
MDL编号:
MFCD00006827
UNSPSC代码:
12352202
PubChem化学物质编号:
57652239
NACRES:
NA.77

质量水平

200

检测方案

≥96.0% (HPLC)

形式

powder

mp

≥300 °C
>300 °C (lit.)

溶解性

ethanol: 10 mg/mL, clear to very faintly turbid, yellow to very deep greenish-yellow

应用

metabolomics
vitamins, nutraceuticals, and natural products

SMILES字符串

Oc1cc(O)c2C(=O)C(O)=C(Oc2c1)c3cc(O)c(O)c(O)c3

InChI

1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H

InChI key

IKMDFBPHZNJCSN-UHFFFAOYSA-N

基因信息

human ... CYP1A2(1544)
mouse ... Hexa(15211)
rat ... Il4(287287) , Tnf(24835)

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相关类别

一般描述

杨梅酮（MYR）一种天然的聚羟基黄烷醇化合物，最早从杨梅树中分离出来。

应用

杨梅酮可用于：
  • 研究其作为抗氧化剂对大鼠噪声性听力损失（NIHL）的预防作用
  • 用作黄酮类化合物测试波旁病毒（BRBV）的抗病毒活性和依赖于 RNA 的 RNA 聚合酶（RdRP）的抑制作用
  • 研究其对变形链球菌和白色念珠菌生物膜的治疗效果
  • 作为刺柏属植物中酚类化合物定量分析的参考标准

生化/生理作用

杨梅酮通过调节多信号通路发挥抗氧化和抗炎作用。此外，它还具有抗糖尿病和保肝作用。 杨梅酮可强烈抑制酵母 α-葡萄糖苷酶、 乙二醛酶 I 体外、和牛乳黄嘌呤氧化酶。此外，它还可促进 DNA 与拓扑异构酶 I 和 II 之间形成络合物，从而可能在癌症化疗中发挥价值。此外，杨梅酮还具有多种营养保健价值和疗效。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

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Xiaominting Song et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 134, 111017-111017 (2020-12-19)
Myricetin(MYR) is a flavonoid compound widely found in many natural plants including bayberry. So far, MYR has been proven to have multiple biological functions and it is a natural compound with promising research and development prospects. This review comprehensively retrieved
Deepak Kumar Semwal et al.
Nutrients, 8(2), 90-90 (2016-02-20)
Myricetin is a common plant-derived flavonoid and is well recognised for its nutraceuticals value. It is one of the key ingredients of various foods and beverages. The compound exhibits a wide range of activities that include strong anti-oxidant, anticancer, antidiabetic
M. Iio, et al.
Agricultural and Biological Chemistry, 48, 1559-1559 (1984)
Guilherme Roncari Rocha et al.
BMC complementary and alternative medicine, 18(1), 61-61 (2018-02-16)
Dental caries is considered a multifactorial disease, in which microorganisms play an important role. The diet is decisive in the biofilm formation because it provides the necessary resources for cellular growth and exopolysaccharides synthesis. Exopolysaccharides are the main components of
Maryam Bahaloo et al.
Iranian journal of otorhinolaryngology, 31(106), 273-279 (2019-10-11)
Exposure to hazardous noise induces one of the forms of acquired and preventable hearing loss that is noise-induced hearing loss (NIHL). Considering oxidative stress as the main mechanism of NIHL, it is possible that myricetin can protect NIHL by its
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商品

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

膳食抗氧化剂

抗氧化剂可保护生物系统免受含氧自由基和氧化还原过渡金属离子（如铁、铜和镉）引起的氧化损伤。

实验方案

HPLC Analysis of Flavonoids on Ascentis® RP-Amide

Protocol for HPLC Analysis of Flavonoids on Ascentis® RP-Amide

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