69293
三氯蔗糖
≥98.0% (HPLC)
别名:
1,6-二氯-1,6-二脱氧 - ＆＃946;-D呋喃果糖基-4-氯-4-脱氧 - ＆＃945;-D-吡喃半乳糖苷, E955, 三氯蔗糖
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关于此项目
经验公式（希尔记法）:
C12H19Cl3O8
化学文摘社编号:
分子量:
397.63
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
259-952-2
Beilstein/REAXYS Number:
3654410
MDL number:
产品名称
三氯蔗糖, ≥98.0% (HPLC)
InChI key
BAQAVOSOZGMPRM-QBMZZYIRSA-N
InChI
1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1
SMILES string
OC[C@H]1O[C@H](O[C@]2(CCl)O[C@H](CCl)[C@@H](O)[C@@H]2O)[C@H](O)[C@@H](O)[C@H]1Cl
assay
≥98.0% (HPLC)
form
powder
optical activity
[α]/D 86.0±2.0°, c = 1 in H2O
sweetness
600 × sucrose
color
white to off-white
useful pH range
6-8 (20 °C, 100 g/L)
mp
114.5 °C ((238.1 °F ) - OECD Test Guideline 102)
solubility
~300 g/L at 25 °C (77 °F)
Quality Level
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Application
三氯蔗糖是一种无热量糖，用作甜味剂，可激活 T1R2/T1R3 甜味受体，调节胰高血糖素样肽-1、葡萄糖依赖性胰岛素营养肽和肠促胰岛素分泌。
Biochem/physiol Actions
一种人类可以检测到的合成甜味剂。可激活肠内分泌细胞上的 T1R2/T1R3 甜味受体，引起胰高血糖素样肽-1 和葡萄糖依赖性胰岛素肽的激素分泌增加。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Nimesh Shukla et al.
Archives of biochemistry and biophysics, 639, 38-43 (2017-12-31)
Sucralose is a commonly employed artificial sweetener that appears to destabilize protein native structures. This is in direct contrast to the bio-preservative nature of its natural counterpart, sucrose, which enhances the stability of biomolecules against environmental stress. We have further
Ana I Domingos et al.
Nature neuroscience, 14(12), 1562-1568 (2011-11-15)
We developed an assay for quantifying the reward value of nutrient and used it to analyze the effects of metabolic state and leptin. In this assay, mice chose between two sippers, one of which dispensed water and was coupled to
Hugo Alarie et al.
International journal of pharmaceutics, 569, 118552-118552 (2019-08-04)
This project aimed to develop a suspension vehicle specifically designed for pediatric use. Excipients were selected according to their safety and recorded use in pediatrics. Two suspension vehicles were formulated at neutral and acidic pH. A few compositions were defined
Shlomi Tamam et al.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 37(3), 520-529 (2012-04-26)
The effect of short duration exercise (EXR) on food intake (FI) and energy balance (EB) is not well understood in either normal weight (NW) or overweight (OW) and obese (OB) 9-14 years old children. Our purpose was to describe the
Tyson A Oberndorfer et al.
The American journal of psychiatry, 170(10), 1143-1151 (2013-06-05)
Recent studies suggest that altered function of higher-order appetitive neural circuitry may contribute to restricted eating in anorexia nervosa and overeating in bulimia nervosa. This study used sweet tastes to interrogate gustatory neurocircuitry involving the anterior insula and related regions
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