产品名称
血红蛋白 来源于牛血液, lyophilized, 2×cryst., ≥90% (SDS-PAGE), powder
biological source
bovine blood
assay
≥90% (SDS-PAGE)
form
powder
quality
2×cryst.
lyophilized
mol wt
Mr ~64500
technique(s)
UV/Vis spectroscopy: suitable
impurities
salt, none detected
~0.3% Fe
loss
≤8% loss on drying
storage temp.
2-8°C
Quality Level
Gene Information
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Application
α-弹性蛋白的溶解度已被应用于弹性蛋白模拟生物材料的构建。
Biochem/physiol Actions
氧气转运蛋白。Fe2+/Fe3+平衡是血液氧合的一种生理指标；脱氧血红蛋白通过将亚硝酸还原为NO来补充反馈回路，而NO是一种可增强血液流向缺氧组织流量的血管扩张剂。
氧转运体，NO 清除剂
Disclaimer
由于天然血红蛋白在空气中易于氧化，因此这些制剂主要为高铁血红蛋白。
General description
Hemoglobin (Hb) is the protein responsible for storage and transport of oxygen and other gaseous ligands in red blood cells (RBC). Hb is also the pioneer material for synthesis of Hb-based oxygen carriers (HBOCs) that can be used as substitutes for RBC.
Other Notes
Review: Oxygen carrier proteins
Sales restrictions may apply
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Paul W Buehler et al.
Biomaterials, 31(13), 3723-3735 (2010-02-13)
Hemoglobin-based oxygen carriers (HBOC) are currently being developed as red blood cell (RBC) substitutes for use in transfusion medicine. Despite significant commercial development, late stage clinical results of polymerized hemoglobin (PolyHb) solutions hamper development. We synthesized two types of PolyHbs
M. Brunori et al.
Topics in Molecular and Structural Biology, 7, 263-263 (1985)
Hiroshi Hori et al.
Journal of inorganic biochemistry, 116, 53-54 (2012-09-27)
The effect of the quaternary structure change in deoxy-Hb on the electronic states of the ferrous high-spin heme was studied by multi-frequency electron paramagnetic resonance (MFEPR). We used a single-pass transmission-type EPR at 70-220 GHz and at 1.5K. We compared
James V Lee et al.
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 199(3), 227-238 (2013-01-17)
Songbirds communicate by learned vocalizations with concomitant changes in neurophysiological and genomic activities in discrete parts of the brain. Here, we tested a novel implementation of diffusive optical imaging (also known as diffuse optical imaging, DOI) for monitoring brain physiology
Shigeru Obayashi et al.
Neuropsychologia, 51(3), 418-424 (2012-12-04)
The supplementary motor area (SMA) has been regarded as a third speech area. The SMA is anatomically classified into two regions, pre-SMA and SMA proper, but the functional specialization of speech production between the two regions remains unknown. Although word
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