所有图片(1)
About This Item
经验公式（希尔记法）:
C21H26O3
CAS号:
分子量:
326.43
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.25
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质量水平
方案
≥98.0% (HPLC)
表单
powder
SMILES字符串
COc1cc(C)c(\C=C\C(C)=C\C=C\C(C)=C\C(O)=O)c(C)c1C
InChI
1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+
InChI key
IHUNBGSDBOWDMA-AQFIFDHZSA-N
基因信息
human ... RARA(5914) , RARB(5915) , RARG(5916) , RXRA(6256) , RXRB(6257) , RXRG(6258)
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应用
阿维 A 是一种可与核受体结合并调节基因表达的类视黄醇，是通过 CD95 信号通路的 α-分泌酶 ADAM10 基因表达和凋亡诱导剂的有效激活剂。 阿维 A 是一种用于治疗严重银屑病的全身性维甲酸类药物。
生化/生理作用
合成维甲酸，是依曲甲酸酯的代谢物。 优先与细胞视黄酸结合蛋白（CRABP） 结合。
警示用语：
Danger
危险分类
Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
储存分类代码
6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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