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Merck
CN
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文件

31404

Sigma-Aldrich

硫酸葡聚糖 钠盐 来源于明串珠菌 属

Mr 5,000

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CAS号:
9011-18-1
MDL编号:
MFCD00081551
UNSPSC代码:
12161700
NACRES:
NA.21

生物来源

(Leuconostoc spp.)

质量水平

200

形式

powder

分子量

Mr 5,000

组成

Sulfur Content, 16.0-20.0%

缺失

≤10% loss on drying

有效pH范围

6.0-8.0 (10 g/L)

溶解性

H2O: 0.1 g/mL, clear, colorless to slightly yellow
water: 100 g/L at 25 °C (77 °F )
H2O: freely soluble 50 mg/mL, clear

储存温度

room temp

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应用

葡聚糖硫酸钠盐来自Leuconostoc sp.，是一种聚合阴离子，作为测试试剂测试它自身的细胞膜外破坏细胞外包裹病毒（EEV）的能力。它还被用来评估TLR4单克隆抗体对于葡聚糖-硫酸盐-钠-（DSS）-引起的大肠炎影响。

生化/生理作用

葡聚糖是不同分子量和形状构成的葡萄糖聚合物的混合物。葡聚糖硫酸钠形式的葡聚糖可用作抗凝血剂。葡聚糖作用于血液凝固因子和血小板功能，感染血液结块形成。它延长了血块形成需要的时间，降低了血凝强度。葡聚糖干扰动态平衡，可能增加流血，加重大肠炎和肾脏衰竭。

制备说明

由 Mr 为 ~5000 的葡聚糖制备

其他说明

为了全面了解我们针对客户研究提供的各种葡聚糖产品，建议您访问我们的碳水化合物分类页面。

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What does Mr refer to on the website product page for Product 31404, Dextran sulfate sodium salt from Leuconostoc spp.?

    Mr stands for relative molecular weight, which is the molecular weight calculated by atomic mass.

  4. How should Dextran sulfate sodium salt from Leuconostoc spp., Product 31404, be stored?

    We would recommend storing this product at room temperature, which is in accordance with our MSDS.

  5. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  6. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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Ulcerative colitis (UC) refers to a kind of inflammatory bowel disease, of which the accurate pathogenesis is not yet well understood. Recently, the toll-like receptor 4 (TLR4) and the TLR4 signaling pathway have been proved as playing an important role
Se Young Choi et al.
Journal of biomedicine & biotechnology, 2010, 943516-943516 (2010-03-20)
A total of 28 male BALB/c mice (average weight 20.7 +/- 1.6 g) were divided into 4 treatment groups and fed a commercial diet (A), a commercial diet + induced colitis by dextran sodium sulfate (DSS) (B), Inonotus obliquus (IO)
Lisa Nebelin Hvidt et al.
Danish medical journal, 59(11), A4531-A4531 (2012-11-23)
Synthetic colloids are frequently used in fluid resuscitation of septic patients. Despite this, little is known about the potential side effects including the risk of renal failure and bleeding. As practice has changed, we performed a before-and-after study of fluid
Prevention of venous thromboembolism.
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The New England journal of medicine, 350(22), 2247-2256 (2004-05-28)
It remains uncertain whether the choice of resuscitation fluid for patients in intensive care units (ICUs) affects survival. We conducted a multicenter, randomized, double-blind trial to compare the effect of fluid resuscitation with albumin or saline on mortality in a
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