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30165

替罗非班

≥98.5% (HPLC)

别名:

N-（丁基磺酰基）-O-[4-（4-哌啶基）丁基]-L-酪氨酸, （2S）-2-（丁基磺酰基氨基）-3-{4-[4-（4-哌啶基）丁氧基}苯基丙酸

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关于此项目

经验公式（希尔记法）:
C22H36N2O5S
化学文摘社编号:
144494-65-5
分子量:
440.60
UNSPSC Code:
12352106
NACRES:
NA.25
PubChem Substance ID:
329753339
MDL number:
MFCD05237246
Beilstein/REAXYS Number:
6182267
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Quality Level

100

assay

≥98.5% (HPLC)

form

powder

SMILES string

CCCCS(=O)(=O)N[C@@H](Cc1ccc(OCCCCC2CCNCC2)cc1)C(O)=O

InChI

1S/C22H36N2O5S/c1-2-3-16-30(27,28)24-21(22(25)26)17-19-7-9-20(10-8-19)29-15-5-4-6-18-11-13-23-14-12-18/h7-10,18,21,23-24H,2-6,11-17H2,1H3,(H,25,26)/t21-/m0/s1

InChI key

COKMIXFXJJXBQG-NRFANRHFSA-N

Gene Information

human ... ITGA2B(3674), ITGB3(3690)

Application


  • The efficacy and safety of continuous intravenous tirofiban for acute ischemic stroke patients treated by endovascular therapy: a meta-analysis.：通过meta分析评估急性缺血性卒中患者血管内治疗中连续静脉给药替罗非班的疗效和安全性，具有改善疗效的满意结果(Wang et al., 2024)。

  • Initial Experience with a New Self-Expanding Open-Cell Stent System with Antithrombotic Hydrophilic Polymer Coating (pEGASUS Stent) in the Treatment of Wide-Necked Intracranial Aneurysms.：研究报道首次用新的涂层支架系统治疗颅内动脉瘤（有用到替罗非班），结果疗效和安全性增强(Boxberg et al., 2024)。

Packaging

无底玻璃瓶。内含物装在插入的融合锥内。

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCM3353
BCCG3999
BCBX5863
BCBX4982
BCBW6811

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Marco Valgimigli et al.
JACC. Cardiovascular interventions, 5(3), 268-277 (2012-03-24)
The authors sought to compare the effect on inhibition of platelet aggregation (IPA) of prasugrel therapy versus tirofiban bolus with or without a post-bolus short drug infusion in ST-segment elevation myocardial infarction (STEMI) patients. The degree and rapidity of IPA
Shukri W David et al.
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 93(5), 882-890 (2018-09-29)
In the randomized AMIHOT-II trial, supersaturated oxygen [SSO2 ] delivered into the left anterior descending (LAD) artery via an indwelling intracoronary infusion catheter following primary percutaneous coronary intervention (PCI) significantly reduced infarct size in patients with anterior ST-segment elevation myocardial
Gang Luo et al.
World neurosurgery, 109, e318-e328 (2017-10-11)
Early recanalization of acute posterior circulation stroke caused by large intracranial vessel occlusion by mechanical thrombectomy with stent retrievers may improve the outcome of patients. However, evidence of patient selection is still lacking. This study investigated the prognostic factors of
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全球贸易项目编号

货号GTIN
30165-5MG04061832860169