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经验公式(希尔记法):
C15H8O5
化学文摘社编号:
分子量:
268.22
UNSPSC Code:
41116107
NACRES:
NA.77
PubChem Substance ID:
EC Number:
207-525-6
Beilstein/REAXYS Number:
266702
MDL number:
Quality Level
assay
≥95.0% (HPLC)
form
powder
impurities
≤10.0% water
mp
≥350 °C (lit.)
SMILES string
Oc1ccc-2c(OC(=O)c3c-2oc4cc(O)ccc34)c1
InChI
1S/C15H8O5/c16-7-1-3-9-11(5-7)19-14-10-4-2-8(17)6-12(10)20-15(18)13(9)14/h1-6,16-17H
InChI key
ZZIALNLLNHEQPJ-UHFFFAOYSA-N
Gene Information
human ... ESR1(2099), ESR2(2100)
mouse ... Esr1(13982)
rat ... Ar(24208)
Application
- 鱼饲料生产中的植物雌激素:香豆雌酚(coumestrol)被用于鱼饲料生产中的生物标志物,有助于评估这些饲料中使用的植物原料 (Pavlopoulos et al., 2023)。
- 考迈斯托醇和大豆叶片衰老: 考察了香豆雌酚(coumestrol)在大豆叶片衰老中的作用,特别是它与植物激素的相互作用,表明了其潜在的农艺效益和在作物科学中的应用,它可作为一种植物抗毒素(Mun et al., 2021)
- 大豆的系统防御本研究考察了香豆雌酚启动(priming )对大豆防御根腐线虫的影响,强调了其作为天然植物防御增强剂的潜力(Adss et al., 2021)。
Biochem/physiol Actions
香豆酚通过雌激素受体-α的介导而对大脑和垂体具有抗雌激素作用。
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
相关内容
Camila Franco et al.
International journal of pharmaceutics, 369(1-2), 5-11 (2008-11-26)
Coumestrol is an estrogenic and antioxidant agent, characterized by its low solubility in aqueous and lipophilic media, once in the aglicone form. In order to improve its solubility in water, coumestrol was associated with beta-cyclodextrin in aqueous media followed by
Bickoff, E.M., et al.
Journal of the American Chemical Society, 80, 3969-3969 (1958)
Michihisa Ueda et al.
Animal science journal = Nihon chikusan Gakkaiho, 83(6), 469-473 (2012-06-15)
The present study was conducted to clarify the effects of coumestrol administration to maternal mice during pregnancy and lactation on serum Ca and Ca metabolism in their neonatal mice. From 6.5 to 16.5 days post coitus and from 3 to
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 27885-50MG | 04061826205068 |
