所有图片(1)
About This Item
线性分子式:
CH3(CH2)13CH(Br)CO2H
CAS号:
分子量:
335.32
Beilstein:
1726517
EC 号:
MDL编号:
UNSPSC代码:
12352203
PubChem化学物质编号:
NACRES:
NA.77
推荐产品
方案
~97%
质量水平
表单
solid
SMILES字符串
CCCCCCCCCCCCCCC(Br)C(O)=O
InChI
1S/C16H31BrO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15(17)16(18)19/h15H,2-14H2,1H3,(H,18,19)
InChI key
DPRAYRYQQAXQPE-UHFFFAOYSA-N
基因信息
human ... PPARD(5467)
正在寻找类似产品? 访问 产品对比指南
一般描述
PPARδ（过氧化物酶体增殖物激活受体，δ 同种型）作为基因表达的一种转录因子，并在脂质代谢调节中发挥作用；该受体的活性受配体调节。2-溴十六烷酸是脂肪酸棕榈酸的代谢稳定的类似物，已被证明是 PPARδ 受体的天然配体。2-溴十六烷酸也已被用在脂肪酸氧化、棕榈酰化和葡萄糖摄取的研究中。
生化/生理作用
溴十六烷酸是 PPARδ 激动剂。它还显示抑制脂肪酸氧化，抑制 DHHC 介导的棕榈酰化，并促进大鼠心脏细胞和胰岛素敏感的鼠成纤维细胞系 A31-IS 中的葡萄糖摄取。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
235.4 °F - closed cup
闪点(°C)
113 °C - closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Joel Berger et al.
Annual review of medicine, 53, 409-435 (2002-01-31)
The peroxisome proliferator-activated receptors (PPARs) are a group of three nuclear receptor isoforms, PPAR gamma, PPAR alpha, and PPAR delta, encoded by different genes. PPARs are ligand-regulated transcription factors that control gene expression by binding to specific response elements (PPREs)
Abiy M Mohammed et al.
Biochemical pharmacology, 85(1), 109-114 (2012-10-25)
Phagocyte-like NADPH oxidase (Nox2) has been shown to play regulatory roles in the metabolic dysfunction of the islet β-cell under the duress of glucolipotoxic conditions and exposure to proinflammatory cytokines. However, the precise mechanisms underlying Nox2 activation by these stimuli
Priyanka Tripathi et al.
Journal of lipid research, 62, 100021-100021 (2021-01-01)
Microtubules are polymers composed of αβ-tubulin subunits that provide structure to cells and play a crucial role in in the development and function of neuronal processes and cilia, microtubule-driven extensions of the plasma membrane that have sensory (primary cilia) or
Kenji Hayata et al.
Journal of pharmacological sciences, 108(3), 348-354 (2008-11-15)
To obtain compounds that promote glucose uptake in muscle cells, the novel cell lines A31-IS derived from Balb/c 3T3 A31 and C2C12-IS from mouse myoblast C2C12 were established. In both cell lines, glucose consumption was induced by insulin and suppressed
Benjamin C Jennings et al.
Journal of lipid research, 50(2), 233-242 (2008-10-02)
Pharmacologic approaches to studying palmitoylation are limited by the lack of specific inhibitors. Recently, screens have revealed five chemical classes of small molecules that inhibit cellular processes associated with palmitoylation (Ducker, C. E., L. K. Griffel, R. A. Smith, S.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门