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Merck
CN

14365C

SAFC

EX-CELL® CD CHO Fusion

Animal-component free, without L-glutamine, without hypoxanthine, without thymidine, liquid, sterile-filtered, suitable for cell culture

Pharma Manufacturing

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别名:
EX-CELL® CD CHO Fusion
UNSPSC代码:
12352207
NACRES:
NA.75

质量水平

无菌性

sterile-filtered

产品线

EX-CELL®

形式

liquid

技术

cell culture | mammalian: suitable (suspension)

组分

L-glutamine: no

运输

ambient

储存温度

2-8°C

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一般描述

EX-CELL® CD CHO FUSION 是一种化学成分确定、不含动物组分的培养基, 是为了中国仓鼠卵巢(CHO)细胞的长期生长而开发。 该 不含任何大分子,所以可用于分离和纯化 细胞 分泌的蛋白质。该培养基不含 L-谷氨酰胺, 这有助于培养基的稳定,避免了L-谷氨酰胺降解所导致的 氨积累, 并为以谷氨酰胺合成酶选择性进行的CHO 细胞培养 (如:MilliporeSigma的CHOZN GS 敲除细胞系)提供合适的培养基。该培养基不含次黄嘌呤或 胸苷 ,因此可以用于二氢叶酸还原酶(DHFR)基因扩增 系统(如:MilliporeSigma的CHOZN DHFR敲除细胞系)

数量

按照 每升培养基20.9克粉末配制。

法律信息

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

动植物来源培养基

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Qiong Wang et al.
Biotechnology and bioengineering, 116(9), 2303-2315 (2019-05-08)
With the increasing demand to provide more detailed quality attributes, more sophisticated glycan analysis tools are highly desirable for biopharmaceutical manufacturing. Here, we performed an intact glycopeptide analysis method to simultaneously analyze the site-specific N- and O-glycan profiles of the
Noriko Yamano-Adachi et al.
Scientific reports, 10(1), 17612-17612 (2020-10-21)
Chinese hamster (Cricetulus griseus) ovary-derived Chinese hamster ovary (CHO) cells are the most commonly used mammalian hosts for the industrial production of recombinant therapeutics because of their ability to fold, assemble, and perform post-translational modifications, such as glycosylation, on proteins.
Weiyi Liu et al.
Biotechnology progress, 37(1), e3061-e3061 (2020-08-05)
Antibody-dependent cellular cytotoxicity (ADCC) is the primary mechanism of actions for several marketed therapeutic antibodies (mAbs) and for many more in clinical trials. The ADCC efficacy is highly dependent on the ability of therapeutic mAbs to recruit effector cells such

商品

This page describes the financial and operational advantages offered by the Cellicon® Cell Retention Device in an N-1 perfusion process at the 2,000 L scale in comparison to a cell retention device from another supplier.

本应用说明描述了Cellvento® 4CHO-X细胞扩增培养基的优势和性能,这款培养基专门开发用于从细胞复苏到N-1阶段的多个细胞扩增步骤,以生成更多生物质接种补料分批生产生物反应器。

How the Cellicon® filter and controller enables seamless adoption of a perfused N-1 seed train step into the cell expansion process.

Cellvento 4CHO-X Expansion Medium enhances cell biomass for bioreactor inoculation in cell expansion stages.

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