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COO原产地证书/COA分析证书

Y0000437

氯苯那敏杂质C

Name: 氯苯那敏杂质C
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

(3RS)-3-(4-Chlorophenyl)-N-methyl-3-(pyridin-2-yl)propan-1-amine

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About This Item

经验公式（希尔记法）:

C₁₅H₁₇ClN₂

CAS号:

20619-12-9

分子量:

260.76

UNSPSC代码:

41116107

NACRES:

NA.24

等级

pharmaceutical primary standard

API类

chlorpheniramine

制造商/商品名称

EDQM

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-8°C

InChI

1S/C15H17ClN2/c1-17-11-9-14(15-4-2-3-10-18-15)12-5-7-13(16)8-6-12/h2-8,10,14,17H,9,11H2,1H3

InChI key

UICFCNIVUDNZSW-UHFFFAOYSA-N

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Chlorphenamine impurity C EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

PHR1647

PHR1688

PHR2004

氯苯那敏杂质A, Pharmaceutical Secondary Standard; Certified Reference Material

BP081

(±)-氯苯那敏马来酸盐, British Pharmacopoeia (BP) Reference Standard

PHR2103

氯苯那敏杂质D, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2104

2-(4-Chlorophenyl)-4-dimethylaminobutyronitrile hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2105

Chlorphenamine N-Oxide Maleate, Pharmaceutical Secondary Standard; Certified Reference Material

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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分析证书(COA)

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Urinary excretion of chlorpheniramine and its metabolites in children.

K J Simons et al.

Journal of pharmaceutical sciences, 73(5), 595-599 (1984-05-01)

The pharmacokinetics and urinary excretion of chlorpheniramine were studied in 11 patients, aged 6-16 years, with allergic rhinitis. In these children, chlorpheniramine had a mean elimination half-life of 13.1 +/- 6.6 h, a mean clearance rate of 7.23 +/- 3.16

Skin permeation of chlorpheniramine maleate and detection of demethylated metabolites by high-performance liquid chromatography.

S Zbaida et al.

Journal of pharmaceutical sciences, 77(2), 188-190 (1988-02-01)

Determination of the enantiomers of chlorpheniramine and its main monodesmethyl metabolite in urine using achiral-chiral liquid chromatography.

B T Hiep et al.

Journal of chromatography. B, Biomedical sciences and applications, 707(1-2), 235-240 (1998-06-05)

The enantiomers of chlorpheniramine and its monodesmethyl metabolite were determined separately in urine by using a coupled achiral-chiral chromatographic system. The two enantiomers of the studied compound and the internal standard were separated from the biological matrix on a cyanopropyl

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