等级
ACS reagent
质量水平
检测方案
≥99.0%
灼烧残渣
≤0.1% (as SO4)
缺失
≤0.5% loss on drying, 105°C, 2h
mp
170-176 °C (lit.)
174-177 °C
溶解性
H2O: passes test
SMILES字符串
NC(N)=S
InChI
1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)
InChI key
UMGDCJDMYOKAJW-UHFFFAOYSA-N
基因信息
mouse ... Ephx2(13850)
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一般描述
硫脲是含尿素硫的类似物。
应用
硫脲已用于:
- 用作肝组织匀浆的裂解缓冲液组分
- 二维凝胶蛋白酪氨酸磷酸酶(PTP)测定所用的二维样品缓冲液
- 蛋白质提取补液缓冲液
离液剂;强变性剂。增加蛋白质的溶解性和回收率
生化/生理作用
硫脲是过氧化物自由基的自由基清除剂。其表现出了抑制脂质过氧化和紫外线(UV)诱导胶原交联的作用。硫脲可用作生长刺激剂,抑制植物芽休眠。目前确知其可用于治疗甲状腺功能亢进症。
警示用语:
Warning
危险分类
Acute Tox. 4 Oral - Aquatic Chronic 2 - Carc. 2 - Repr. 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
危险化学品
Investigation of protein-tyrosine phosphatases by in-gel assays.
Methods, 35(1), 22-27 (2005)
Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches
Aquaculture and Fisheries, 1(2), 15-23 (2016)
Mechanism of the reduction of methylene blue by thiourea in aqueous acidic medium
International Journal of ChemTech Research, 4(2), 609-617 (2012)
Chemical & pharmaceutical bulletin, 58(5), 593-601 (2010-05-13)
We have developed several multifunctional thiourea catalysts bearing a tertiary amine or an 1,2-amino alcohol in expectation of their synchronous activation of a nucleophile and an electrophile through both acid-base and hydrogen-bonding interactions. From these studies, it was revealed that
Macromolecular rapid communications, 34(8), 652-658 (2013-03-14)
Readily water-soluble PEGylated amphiphiles containing bis-thiourea-based molecular recognition units at the interface of hydrophobic and hydrophilic blocks are developed. Self-assembly of these amphiphiles is found to be dependent on the exact chemical composition of the hydrophobic component. Elongated, spherical, and
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