S7920
氟化钠
BioXtra, ≥99%
别名:
NaF, Natrium fluoride, Sodium monoflouride
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关于此项目
线性分子式:
NaF
化学文摘社编号:
分子量:
41.99
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352302
EC Number:
231-667-8
MDL number:
Assay:
≥99%
Solubility:
H2O: 1 M, clear, colorless
产品名称
氟化钠, BioXtra, ≥99%
InChI key
PUZPDOWCWNUUKD-UHFFFAOYSA-M
InChI
1S/FH.Na/h1H;/q;+1/p-1
SMILES string
[F-].[Na+]
vapor pressure
1.4 mmHg ( 0 °C)
product line
BioXtra
assay
≥99%
impurities
≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter
mp
993 °C (lit.)
solubility
H2O: 1 M, clear, colorless
anion traces
chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.03%
cation traces
Al: ≤0.001%
Ca: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.003%
K: ≤0.02%
Mg: ≤0.0005%
NH4+: ≤0.1%
Pb: ≤0.001%
Zn: ≤0.0005%
Quality Level
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Biochem/physiol Actions
氟化钠（NaF）通过催化钙和磷酸盐的扩散和使病灶再矿化来预防龋齿。氟化物影响女性生殖道的精子发生和获能过程。氟化物诱导氧化应激，卵巢中的 DNA 损伤最终会影响卵母细胞的发育。补充氟化物可以增强骨矿物质密度。18F-NaF 是一种放射性示踪剂，用于通过正电子发射断层扫描（PET）识别动脉粥样硬化病变和其他心脏斑块。
Other Notes
Application
氟化钠已被用于：
- 作为氟离子的来源，分析其对体外精子发生和获能的影响
- 作为提取缓冲液中的添加剂，用于分离细胞核、细胞质和核蛋白
- 作为裂解缓冲液的组分，用于裂解人卵巢腺癌 OVCAR3 细胞
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2
supp_hazards
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
法规信息
危险化学品
此项目有
Effects of treatment with fluoride on bone mineral density and fracture risk-a meta-analysis
Vestergaard P, et al.
Osteoporosis International : A Journal Established as Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 19(3), 257-268 (2008)
Fluoride-induced oxidative stress and apoptosis are involved in the reducing of oocytes development potential in mice
Wang HW, et al.
Chemosphere, 186, 911-918 (2017)
Dental caries
Selwitz RH, et al.
Lancet, 369(9555), 51-59 (2007)
Mangiferin induces apoptosis in human ovarian adenocarcinoma OVCAR3 cells via the regulation of Notch3
Zou B, et al.
Oncology Reports, 38(3), 1431-1441 (2017)
Merging high-quality biochemical fractionation with a refined flow cytometry approach to monitor nucleocytoplasmic protein expression throughout the unperturbed mammalian cell cycle
Rosner M, et al.
Nature Protocols, 8(3), 602-602 (2013)
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