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PHR1724

氟哌啶醇

Name: 氟哌啶醇
Brand: SIAL

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

氟哌啶醇, 4-[4-（4-氯苯基）-4-羟基-1-哌啶基]-1-（4-氟苯基）-1-丁酮, 4-[4-（4-氯苯基）-4-羟基哌啶基]-4'-氟丁酰苯, 4-[4-（对氯苯基）-4-羟基哌啶基]-4'-氟丁酰苯

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About This Item

经验公式（希尔记法）:

C₂₁H₂₃ClFNO₂

CAS号:

52-86-8

分子量:

375.86

EC 号:

200-155-6

MDL编号:

MFCD00051423

UNSPSC代码:

41116107

PubChem化学物质编号:

329823577

NACRES:

NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

300

Agency

traceable to BP 407
traceable to Ph. Eur. H0100000
traceable to USP 1303002

API类

haloperidol

CofA

current certificate can be downloaded

包装

pkg of 400 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

格式

neat

储存温度

2-30°C

SMILES字符串

OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Cl)cc3

InChI

1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2

InChI key

LNEPOXFFQSENCJ-UHFFFAOYSA-N

基因信息

human ... HTR2A(3356)

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一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Haloperidol is a major tranquilizer that is indicated for the treatment of schizophrenia, mania and neurological disorders including hyperkinesia.

应用

Haloperidol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC) and spectrophotometry techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAB7792 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

1303013

1303057

Haloperidol decanoate, United States Pharmacopeia (USP) Reference Standard

1303024

BP407

氟哌啶醇, British Pharmacopoeia (BP) Reference Standard

PHR8951

PHR8714

象形图

GHS06,GHS08

警示用语：

Danger

危险声明

H301,H315,H317,H319,H335,H361

预防措施声明

P202 - P261 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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分析证书(COA)

Lot/Batch Number

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Determination and degradation study of haloperidol by high performance liquid chromatography.

Trabelsi H, et al.

Journal of Pharmaceutical and Biomedical Analysis, 29(4), 649-657 (2002)

Quantitative high performance liquid chromatographic determination of bamipine combined with tricyclic antidepressants and/or antipsychotics in pharmaceutical formulations.

Kountourellis JE, et al.

Analytical Letters, 26(10), 2171-2182 (1993)

Validation of derivative spectrophotometry method for determination of active ingredients from neuroleptics in pharmaceutical preparations.

Stolarczyk M, et al.

Acta Poloniae Pharmaceutica, 66(4), 351-356 (2009)

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