PHR1679
盐酸托莫西汀
Pharmaceutical Secondary Standard; Certified Reference Material
别名:
（R）-托莫西汀 盐酸盐, 盐酸托莫西汀 盐酸盐, （R）-N-甲基-γ-（2-甲基苯氧基）苯丙胺 盐酸盐
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关于此项目
经验公式（希尔记法）:
C17H21NO · HCl
化学文摘社编号:
分子量:
291.82
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
产品名称
盐酸托莫西汀, Pharmaceutical Secondary Standard; Certified Reference Material
InChI
1S/C17H21NO.ClH/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15;/h3-11,17-18H,12-13H2,1-2H3;1H/t17-;/m1./s1
SMILES string
CNCC[C@@H](OC1=CC=CC=C1C)C2=CC=CC=C2.[H]Cl
InChI key
LUCXVPAZUDVVBT-UNTBIKODSA-N
grade
certified reference material
pharmaceutical secondary standard
agency
traceable to Ph. Eur. Y0001586
traceable to USP 1044469
API family
atomoxetine
CofA
current certificate can be downloaded
packaging
pkg of 500 mg
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
Quality Level
Gene Information
human ... SLC6A2(6530)
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Biochem/physiol Actions
去甲肾上腺素摄取阻滞剂。
Analysis Note
These secondary standards offer multi-traceability to the USP and EP primary standards, where they are available.
Application
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Atomoxetine hydrochloride may be used as a pharmaceutical reference standard for the determination of atomoxetine hydrochloride in pharmaceutical formulations by spectrophotometric method.
Atomoxetine hydrochloride may be used as a pharmaceutical reference standard for the determination of atomoxetine hydrochloride in pharmaceutical formulations by spectrophotometric method.
General description
Atomoxetine hydrochloride is a nonstimulant used in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in children and adults.
Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Other Notes
Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA6124 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Colourimetric assay of atomoxetine hydrochloride by simple aurum coupling reaction in bulk and tablet dosage form.
Ishaq B M, et al.
Global Journal of Medical research, 13(7B) (2014)
Joshua Caballero et al.
Clinical therapeutics, 25(12), 3065-3083 (2004-01-30)
Attention-deficit/hyperactivity disorder (ADHD) occurs in approximately 3% to 10% of the pediatric population. Most of the drugs typically used to treat ADHD are stimulants, which, because of their addictive properties and potential for abuse, are controlled substances. Although these drugs
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