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Merck
CN

PHR1504

Supelco

3,3′,5-三碘代-L-甲状腺原氨酸

Pharmaceutical Secondary Standard; Certified Reference Material

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别名:
O-(4-羟基-3-碘苯基)-3,5-二碘代-L-酪氨酸, T3, 碘噻罗宁
经验公式(希尔记法):
C15H12I3NO4
CAS号:
分子量:
650.97
Beilstein:
2710227
EC 号:
MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
NACRES:
NA.24

等级

certified reference material
pharmaceutical secondary standard

质量水平

Agency

traceable to USP 1368008

API类

liothyronine

形式

solid

CofA

current certificate can be downloaded

包装

pkg of 500 mg

技术

HPLC: suitable
gas chromatography (GC): suitable

mp

234-238 °C (lit.)

应用

pharmaceutical (small molecule)

储存温度

2-8°C

SMILES字符串

N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O

InChI

1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

InChI key

AUYYCJSJGJYCDS-LBPRGKRZSA-N

基因信息

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一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC2088 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

STOT RE 1

靶器官

Thyroid,Cardio-vascular system,Kidney

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

分析证书(COA)

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Aoife Parsons et al.
Aquatic toxicology (Amsterdam, Netherlands), 209, 99-112 (2019-02-15)
Brominated flame retardants are known to disrupt thyroid hormone (TH) homeostasis in several vertebrate species, but the molecular mechanisms underlying this process and their effects on TH-sensitive tissues during the stages of early development are not well characterised. In this

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