跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

PHR1055

Supelco

法莫替丁

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

N′-（氨基磺酰基）-3-([2-（二氨基亚甲基氨基）-4-噻唑基]甲硫基)丙脒

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C8H15N7O2S3
CAS号:
76824-35-6
分子量:
337.45
MDL编号:
MFCD00079297
UNSPSC代码:
41116107
PubChem化学物质编号:
329823085
NACRES:
NA.24

生物来源

synthetic

质量水平

300

等级

certified reference material
pharmaceutical secondary standard

Agency

BP
EP
USP
traceable to BP 653
traceable to Ph. Eur. F0050000
traceable to USP 1269200

蒸汽压

<0.0000001 kPa ( 25 °C)

API类

famotidine

CofA

current certificate can be downloaded

包装

pkg of 1 g

储存条件

protect from light (20 mm aluminium crimp seal for unused portion)

技术

HPLC: suitable
gas chromatography (GC): suitable

颜色

white to pale yellow-white

mp

325.4-327.2 °F (163—164°C)

溶解性

DMF: freely soluble
acetone: practically insoluble
chloroform: practically insoluble
ethanol: practically insoluble
ether: practically insoluble
ethyl acetate: practically insoluble
glacial acetic acid: freely soluble
methanol: slightly soluble
water: very slightly soluble

应用

pharmaceutical (small molecule)

包装形式

neat

运输

ambient

储存温度

2-8°C

SMILES字符串

N\C(N)=N\c1nc(CSCCC(=N)NS(N)(=O)=O)cs1

InChI

1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)

InChI key

XUFQPHANEAPEMJ-UHFFFAOYSA-N

基因信息

human ... HRH2(3274)

正在寻找类似产品? 访问 产品对比指南

相关类别

一般描述

Famotidine is a histamine H2-receptor antagonist, which promotes the healing of erosive esophagitis, gastric and duodenal ulcers since it inhibits the gastric acid secretion in humans.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Famotidine may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using different chromatography techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

生化/生理作用

H2组胺受体拮抗剂；抗溃疡剂。

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA7133 in the slot below. This is an example certificate only and may not be the lot that you receive.

相关产品

产品编号
说明
价格

F0005000

法莫替丁, European Pharmacopoeia (EP) Reference Standard

Y0000409

法莫替丁杂质D, European Pharmacopoeia (EP) Reference Standard

Y0000382

法莫替丁, European Pharmacopoeia (EP) Reference Standard

1269200

法莫替丁, United States Pharmacopeia (USP) Reference Standard

1269243

Famotidine Related Compound D, United States Pharmacopeia (USP) Reference Standard

1269265

Famotidine Related Compound F, United States Pharmacopeia (USP) Reference Standard

1269221

Famotidine Related Compound B, United States Pharmacopeia (USP) Reference Standard

1269232

Famotidine Related Compound C, United States Pharmacopeia (USP) Reference Standard

1269254

Famotidine Related Compound E, United States Pharmacopeia (USP) Reference Standard

BP653

法莫替丁, British Pharmacopoeia (BP) Reference Standard

PHR2908

Famotidine Related Compound F, certified reference material, pharmaceutical secondary standard

PHR2909

Famotidine Related Compound B, certified reference material, pharmaceutical secondary standard

PHR2910

Famotidine Related Compound C

PHR2911

Famotidine Related Compound D

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

The
Profiles of Drug Substances, Excipients, and Related Methodology (2011)
GC Determination of famotidine, ranitidine, cimetidine, and metformin in pharmaceutical preparations and serum using methylglyoxal as derivatizing reagent
Majidano AS, et al.
Chromatographia, 75(21-22), 1311-1317 (2012)
S Takayama et al.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 63(1), 41-52 (2012-03-31)
We set up a new model of gastric bleeding induced by the luminal perfusion of aspirin (ASA) in rats pretreated with clopidogrel under conditions where acid secretion is stimulated, and examined the effect of antiulcer drugs on the bleeding. Under
Hideto Yano et al.
Circulation journal : official journal of the Japanese Circulation Society, 76(11), 2673-2680 (2012-08-07)
It remains unclear whether concomitant use of omeprazole attenuates platelet function as compared with that of famotidine in patients with acute coronary syndromes (ACS) who receive clopidogrel. In this prospective study, 130 ACS patients treated with aspirin and clopidogrel who
Kenichi Yamamoto et al.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 30(12), 1958-1962 (2012-05-18)
Heterotopic ossification or calcification follows any type of musculoskeletal trauma and is known to occur after arthroplasties of hip, knee, shoulder, or elbow; fractures; joint dislocations; or tendon ruptures. Histamine receptor H2 (Hrh2) has been shown to be effective for
查看所有相关文献

相关内容

最新推出的满足海关审查要求的标准物质

默克Supelco®标准物质不断推出或更新满足海关及法规要求的标准物质。每年我们约有上百种的新CRM或标准物质上市，在此我们尽可能多的列出满足海关及法规要求的标准物质。

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门