推荐产品
生物来源
synthetic (organic)
质量水平
Agency
USP/NF
meets USP testing specifications
检测方案
98.5-101.5% dry basis
形式
crystals
颜色
white
mp
128-131 °C (lit.)
应用
pharmaceutical (small molecule)
SMILES字符串
NC(=O)c1cccnc1
InChI
1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
InChI key
DFPAKSUCGFBDDF-UHFFFAOYSA-N
基因信息
human ... PARP1(142) , SIRT2(22933)
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一般描述
烟酰胺，也称为3-吡啶甲酰胺，是水溶性维生素。在植物、动物性食品和化妆品中广泛存在。
应用
烟酰胺用于：
- 作为胰岛成熟培养基的组分
- 诱导胰岛素分泌细胞分化
- 比较其与孕酮的临床前疗效
生化/生理作用
烟酰胺是烟酰胺腺嘌呤二核苷酸（NAD+）的主要前体，而NAD+是三磷酸腺苷（ATP）产生过程中的重要辅酶。 烟酰胺缺乏与糙皮病有关。
烟酰胺是维生素B3的酰胺衍生物，是PARP抑制剂
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
WGK
WGK 1
闪点(°F)
closed cup
闪点(°C)
closed cup
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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Stimulatory Role of Glycated Fetal Bovine Serum Along with Iron on In Vitro Production of Insulin by Differentiated Mouse Embryonic Stem Cells
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Role of nicotinamide in DNA damage, mutagenesis, and DNA repair
Surjana D, et al.
Journal of Nucleic Acids, 2010 (2010)
Robert J Motzer et al.
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In a phase 3 trial comparing the efficacy and safety of axitinib versus sorafenib as second-line treatment for metastatic renal cell carcinoma, patients given axitinib had a longer progression-free survival (PFS). Here, we report overall survival and updated efficacy, quality
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