Agency
USP/NF
meets USP testing specifications
质量水平
应用
pharmaceutical (small molecule)
储存温度
2-8°C
SMILES字符串
COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCCCC3
InChI
1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)
InChI key
ZNNLBTZKUZBEKO-UHFFFAOYSA-N
基因信息
human ... ABCC8(6833) , KCNH2(3757) , KCNJ11(3767)
rat ... Kcnj1(24521)
正在寻找类似产品? 访问 产品对比指南
危险声明
预防措施声明
危险分类
Aquatic Chronic 4
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Ruchira M Jha et al.
Journal of neurotrauma, 38(5), 628-645 (2020-11-19)
Glibenclamide (GLY) is the sixth drug tested by the Operation Brain Trauma Therapy (OBTT) consortium based on substantial pre-clinical evidence of benefit in traumatic brain injury (TBI). Adult Sprague-Dawley rats underwent fluid percussion injury (FPI; n = 45), controlled cortical impact (CCI;
Jesse A Stokum et al.
Science signaling, 16(788), eadd6364-eadd6364 (2023-06-06)
Brain swelling causes morbidity and mortality in various brain injuries and diseases but lacks effective treatments. Brain swelling is linked to the influx of water into perivascular astrocytes through channels called aquaporins. Water accumulation in astrocytes increases their volume, which
Lisa D Marroquin et al.
Current protocols in toxicology, 71, 14-14 (2017-02-02)
The bile salt export pump (BSEP, ABCB11) belongs to the ATP-binding-cassette superfamily of transporters and is predominately found in the liver. BSEP is an efflux transporter that plays a critical role in the secretion of bile salts into the bile.
Khac-Minh Thai et al.
Bioorganic & medicinal chemistry, 16(7), 4107-4119 (2008-02-05)
Acquired long QT syndrome causes severe cardiac side effects and represents a major problem in clinical studies of drug candidates. One of the reasons for development of arrhythmias related to long QT is inhibition of the human ether-a-go-go-related-gene (hERG) potassium
The effect of Glibenclamide on somatosensory evoked potentials after cardiac arrest in rats.
Lachance, et al.
Neurocritical Care, 36, 612-620 (2023)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门