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D1435

Sigma-Aldrich

二甲基亚砜

meets EP testing specifications, meets USP testing specifications

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别名:
DMSO, 甲基亚砜
线性分子式:
(CH3)2SO
CAS号:
67-68-5
分子量:
78.13
Beilstein:
506008
EC 号:
200-664-3
MDL编号:
MFCD00002089
UNSPSC代码:
12191502
PubChem化学物质编号:
57654071
NACRES:
NA.71

Agency

meets EP testing specifications
meets USP testing specifications

质量水平

200

蒸汽密度

2.7 (vs air)

蒸汽压

0.42 mmHg ( 20 °C)

检测方案

≥99.5%

形式

liquid

自燃温度

573 °F

expl. lim.

42 %, 63 °F

技术

cryopreservation: suitable

杂质

≤0.1% water (Karl Fischer, USP)
≤0.2% water (Karl Fischer, EP)

颜色

colorless

折射率

n20/D 1.478-1.479
n20/D 1.479 (lit.)

bp

189 °C (lit.)

mp

16-19 °C (lit.)

溶解性

H2O: miscible (completely)

密度

1.100-1.104 g/mL at 25 °C (relative density (EP))
1.10 g/mL (lit.)

紫外吸收

λ: 285 nm Amax: ≤0.20
λ: 295 nm Amax: ≤0.20

SMILES字符串

CS(C)=O

InChI

1S/C2H6OS/c1-4(2)3/h1-2H3

InChI key

IAZDPXIOMUYVGZ-UHFFFAOYSA-N

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应用

二甲亚砜已用于：
  • 溶解四甲基罗丹明染料，从而用作荧光原位杂交（FISH）实验的荧光团
  • 用作猪睾丸(ST)细胞间接免疫荧光测定（IFA）的对照物
  • 颊细胞悬浮和分离
  • 聚合酶链式反应(PCR)的极性非质子溶剂，同时可用作冷冻保护剂玻璃化剂，用于保存细胞、组织和器官。

生化/生理作用

二甲基亚砜（DMSO）是一种低分子量、低亲水性且可自由透膜的防冻剂。它是一种聚合酶链式反应(PCR)的极性非质子溶剂，同时可用作冷冻保护剂玻璃化剂，用于保存细胞、组织和器官。

注意

在室温下容易过冷并缓慢重融。 固化产品可以通过加热至室温来重新液化，而不会损害产品。

其他说明

有关二甲基亚砜混溶性的信息，请访问以下链接：
二甲基亚砜混溶性/不混溶性表格

相关产品

产品编号
说明
价格

WGK

WGK 1

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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  1. What is the molarity of DMSO?

    DMSO will have a molarity of 14.1M, based on a density of 1.1 g/mL and a molecular weight of 78.13 g/mol.

  2. What is the DMSO dissolved in?

    DMSO is not dissolved in any solvent. It is a pure chemical compound that is a liquid at room temperature.

  3. Where does DMSO come from?

    DMSO is known to have been isolated from tree bark in the past. It is now a commericially synthesized solvent.

  4. Does DMSO have any synthetic utility?

    DMSO has been used to oxidize thiols and disulfides to sulfonic acids, hydrolysis of epoxides, thioalkylation of phenols, and oxidation of primary alcohols and halides, and esters of primary alcohols to aldehydes.

  5. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  6. Dimethyl sulfoxide (DMSO) should be a liquid.  Why did it arrive as a solid?

    DMSO supercools easily, and re-melts slowly at room temperature. The melting point is 16-19 °C. The solidified product can be re-liquefied by warming to room temperature without detriment to the product.

  7. What is the difference between Dimethyl sulfoxide (DMSO) Products. D1435 and D2438?

    Products D1435 and D2438 both meet the USP specifications. The D2438 is sterile-filtered, but D1435 is not. Furthermore, the D2438 is quality control tested for endotoxin and use-tested for cell freezing.

  8. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  9. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  10. Is Dimethyl sulfoxide a sterile product?

    No, this product is not considered sterile.  Product Nos. D2560 and D2438 are sterile-filtered.

  11. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  12. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Identification of anti-viral activity of the cardenolides, Na+/K+-ATPase inhibitors, against porcine transmissible gastroenteritis virus
Yang CW, et al.
Toxicology and Applied Pharmacology, 332, 129-137 (2017)
Low dose dimethyl sulfoxide driven gross molecular changes have the potential to interfere with various cellular processes
Tunccer S, et al.
Scientific reports, 8(1), 14828-14828 (2018)
Single-molecule mRNA detection and counting in mammalian tissue
Lyubimova A, et al.
Nature Protocols, 8(9), 1743-1743 (2013)
Buccal micronucleus cytome assay: results of an intra-and inter-laboratory scoring comparison
Bolognesi C, et al.
Mutagenesis, 30(4), 545-555 (2015)
Comparison of the effects of different cryoprotectants on stem cells from umbilical cord blood
Chen G, et al.
Stem Cells International, 2016 (2016)
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