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等级
pharmaceutical primary standard
API类
diclofenac
制造商/商品名称
EDQM
技术
HPLC: suitable
gas chromatography (GC): suitable
应用
pharmaceutical (small molecule)
格式
neat
InChI
1S/C14H11Cl2NO2.K/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19;/h1-7,17H,8H2,(H,18,19);/q;+1/p-1
InChI key
KXZOIWWTXOCYKR-UHFFFAOYSA-M
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一般描述
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
应用
Diclofenac potassium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
包装
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
其他说明
Sales restrictions may apply.
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产品编号
说明
价格
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Aquatic Chronic 2
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Drugs, 57(6), 991-1003 (1999-07-10)
The NSAID diclofenac is a potent inhibitor of prostaglandin synthesis and an established antipyretic and analgesic agent. Diclofenac-potassium was developed as an immediate-release tablet with the aim of providing rapid onset of action after oral administration. This formulation has been
Clinical drug investigation, 27(3), 163-195 (2007-02-20)
Non-prescription (over-the-counter [OTC]) analgesics are used for the short-term treatment of acute painful conditions of mild to moderate intensity in everyday life. Well documented safety and efficacy, a rapid onset of action and a flexible daily dosing regimen are essential
Toxicology and applied pharmacology, 269(2), 141-149 (2013-03-20)
Diclofenac (DF) is a widely used non-steroidal anti-inflammatory drug for the treatment of rheumatic disorders, but is often associated with liver injury. We applied urinary proteomic profiling using MALDI-TOF MS to identify biomarkers for DF-induced hepatotoxicity in mice. Female CH3/HeOUJIco
The Science of the total environment, 506-507, 252-258 (2014-12-03)
The reaction kinetics and toxicity of diclofenac (DCF) oxidation by ferrate (VI) under simulated water disinfection conditions were investigated. Experimental results indicated that the reaction between DCF and Fe(VI) followed first-order kinetics with respect to each reactant. Furthermore, the effects
Environmental toxicology and pharmacology, 35(3), 454-460 (2013-03-19)
Diclofenac residues have been found in surface water, and thus could present a potential risk to aquatic species. The aim of this study was to assess the impact of diclofenac on the mortality, growth, and development of fish, as well
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