InChI key
RKWGIWYCVPQPMF-UHFFFAOYSA-N
InChI
1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)
SMILES string
CCCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1
grade
analytical standard
assay
≥97%
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
Quality Level
Gene Information
human ... ABCC8(6833), ALB(213), EPHX2(2053), KCNJ1(3758), KCNJ11(3767)
mouse ... Ephx2(13850)
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General description
Chlorpropamide is a drug that belongs to the sulfonylurea family. It is an effective candidate in the treatment of diabetes insipidus.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
Worst Pills, Best Pills: A Consumer's Guide to Preventing Drug-Induced Deat (2009)
Advances in Clinical Chemistry, Volume 17 (1975)
Qing Zhu et al.
Molecular pharmaceutics, 7(4), 1291-1300 (2010-06-17)
As a result of an increase in the number of emerging therapies with dissolution limited bioavailability, formulation strategies such as solid dispersions that enhance the rate of solubilization are of interest. In this study, the microstructure of solid dispersions prepared
Terence M Williams et al.
Molecular cancer therapeutics, 11(5), 1193-1202 (2012-03-14)
There is an urgent need for the development of novel therapies to treat pancreatic cancer, which is among the most lethal of all cancers. KRAS-activating mutations, which are found in more than 90% of pancreatic adenocarcinomas, drive tumor dependency on
Jer-Yen Yang et al.
Cancer research, 70(11), 4709-4718 (2010-05-21)
Drug resistance is a central challenge of cancer therapy that ultimately leads to treatment failure. In this study, we characterized a mechanism of drug resistance that arises to AZD6244, an established mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) 1/2 inhibitor currently
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