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等级
certified reference material
TraceCERT®
质量水平
产品线
TraceCERT®
保质期
limited shelf life, expiry date on the label
制造商/商品名称
Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
储存条件
under inert gas
技术
HPLC: suitable
gas chromatography (GC): suitable
mp
173-175 °C (lit.)
应用
food and beverages
包装形式
neat
SMILES字符串
COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1
InChI
1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1
InChI key
LOUPRKONTZGTKE-WZBLMQSHSA-N
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一般描述
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
生化/生理作用
钾通道阻断剂。
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
注意
Store under argon.
法律信息
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral - Skin Sens. 1
储存分类代码
11 - Combustible Solids
WGK
WGK 1
法规信息
监管及禁止进口产品
George Praygod et al.
Malaria journal, 7, 210-210 (2008-10-22)
The efficacy of intravenous quinine, which is the mainstay for treating severe malaria in children, is decreasing in South East Asia and Africa. Artemisinin derivatives are a potential alternative to quinine. However, their efficacy compared to quinine in treating severe
Hmwe Hmwe Kyu et al.
Bulletin of the World Health Organization, 87(12), 896-904 (2010-05-11)
To summarize the existing evidence on the efficacy of artemether and arteether, two artemisinin derivatives, versus quinine for treating cerebral malaria in children. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and the http://clinicaltrials.gov web site. We
Jane Achan et al.
Malaria journal, 10, 144-144 (2011-05-26)
Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex dosing regimens, and the availability of more efficacious anti-malarial drugs. This
Xiong-Li Liu et al.
Organic letters, 15(6), 1246-1249 (2013-03-05)
A wide range of structurally diverse 3,3'-thiopyrrolidonyl spirooxindoles bearing three contiguous stereogenic centers can be smoothly obtained via a domino Michael/cyclization reaction between 3-isothiocyanato oxindoles and 3-methyl-4-nitro-5-alkenyl-isoxazoles with commercially available quinine as the catalyst under mild conditions. The protocol is
Joop E Arends et al.
The American journal of tropical medicine and hygiene, 89(3), 527-530 (2013-07-17)
Recently, two patients of African origin were given a diagnosis of Plasmodium falciparum malaria without recent travel to a malaria-endemic country. This observation highlights the importance for clinicians to consider tropical malaria in patients with fever. Possible transmission routes of
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