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Merck
CN

59964

Supelco

组胺

analytical standard

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别名:
2-(4-咪唑基)乙胺
经验公式(希尔记法):
C5H9N3
CAS号:
分子量:
111.15
Beilstein:
2012
EC 号:
MDL编号:
UNSPSC代码:
85151701
PubChem化学物质编号:
NACRES:
NA.24

等级

analytical standard

质量水平

检测方案

≥97.0% (TLC)
≥97.0% (anhydrous basis, NT)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

杂质

≤4.0% water

颜色

white to light yellow

bp

167 °C/0.8 mmHg (lit.)

mp

83-84 °C (lit.)

格式

neat

储存温度

−20°C

SMILES字符串

NCCc1c[nH]cn1

InChI

1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)

InChI key

NTYJJOPFIAHURM-UHFFFAOYSA-N

基因信息

human ... HRH1(3269)

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应用

有关理想仪器技术的更多信息,参见产品#8242;s分析证书。想要获得更多支持,请联系技术服务部。

生化/生理作用

内源性 H1 和 H2 组胺受体激动剂;H1 的活化可以使 Ca2+ 移动;H2 的活化可促进神经元中腺苷酸环化酶的活性;活化一氧化氮合成酶;有效的血管舒张剂。

象形图

Skull and crossbonesHealth hazard

警示用语:

Danger

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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P J Turner et al.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 25(7), 657-661 (2014-10-10)
Most children with egg allergy tolerate egg in baked foods, such as cake, but tolerance cannot be predicted with conventional allergy testing. We hypothesized that the skin prick test (SPT) wheal to unprocessed raw egg might predict tolerance of baked
Ye Zhang et al.
Investigative ophthalmology & visual science, 56(1), 563-570 (2015-01-13)
We estimate and compare change in iris cross-sectional area (IA) after physiologic and pharmacologic mydriasis in subjects with different dominant mechanisms for primary angle closure. Anterior segment optical coherence tomography (AS-OCT) measurements in light, dark, and following pharmacologic dilation were
W Tang et al.
Oncogene, 33(20), 2629-2638 (2013-06-12)
Recent studies suggested that cancer stem cells (CSCs) are capable of differentiating into endothelial cells and tumor endothelium may be derived from CSCs. But the mechanism remains unclear. We showed that vascular endothelial growth factor (VEGF) induced the expression of
Katsuya Nagai et al.
Amino acids, 43(1), 97-109 (2012-03-01)
L-carnosine (β-alanyl-L-histidine; CAR) is synthesized in mammalian skeletal muscle. Although the physiological roles of CAR have not yet been clarified, there is evidence that the release of CAR from skeletal muscle during physical exercise affects autonomic neurotransmission and physiological functions.
Mohamed H Shamji et al.
The Journal of allergy and clinical immunology, 135(4), 913-921 (2014-12-03)
Immunotherapy inhibits basophil histamine release, but the assay is cumbersome, and no one has studied the effects of immunotherapy withdrawal. Intracellular fluorochrome-labeled diamine oxidase (DAO) was used as a novel functional readout of basophil histamine release after immunotherapy. Results were

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