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Merck
CN
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文件

安全信息

46923

Supelco

睾酮

VETRANAL®, analytical standard

别名:

17β-羟基-3-氧代-4-雄甾烯, 17β-羟基-4-雄甾烯-3-酮, 4-雄甾烯β-17-醇-3-酮, 反式睾酮

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About This Item

经验公式（希尔记法）:
C19H28O2
CAS号:
58-22-0
分子量:
288.42
Beilstein:
1915399
EC 号:
200-370-5
MDL编号:
MFCD00003654
UNSPSC代码:
41116107
PubChem化学物质编号:
329757265
NACRES:
NA.24

等级

analytical standard

质量水平

100

产品线

VETRANAL®

保质期

limited shelf life, expiry date on the label

药品控制

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

技术

HPLC: suitable
gas chromatography (GC): suitable

溶解性

H2O: soluble

应用

forensics and toxicology
pharmaceutical (small molecule)

格式

neat

SMILES字符串

C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O

InChI

1S/C19H28O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-17,21H,3-10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1

InChI key

MUMGGOZAMZWBJJ-DYKIIFRCSA-N

基因信息

human ... AR(367)

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相关类别

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化/生理作用

睾丸分泌的睾酮在目标组织中转变为双氢睾酮，介导睾酮的多种生物作用。雄激素诱导胚胎发生和青春期的男性表型发育。

法律信息

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Repr. 1B

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

个人防护装备

Eyeshields, Gloves, type P2 (EN 143) respirator cartridges

法规信息

监管及禁止进口产品

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number
BCCF3787
BCBS8823V
SZBD238XV
SZBA235XV
SZBA235X

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James R Bell et al.
American journal of physiology. Heart and circulatory physiology, 306(9), H1265-H1274 (2014-03-13)
Estrogen in females is conventionally considered a cardioprotective influence, but a role for estrogen in male cardioprotection has yet to be defined. Estrogen biosynthesis from testosterone is regulated by aromatase. Aromatase has recently been shown to be expressed in the
Andrea C Lo et al.
International journal of radiation oncology, biology, physics, 88(1), 87-93 (2013-12-18)
To determine (1) the prognostic utility of prostate-specific antigen (PSA) concentration at 45 to 60 months (48mPSA) after low-dose-rate prostate brachytherapy (LDR-PB); (2) the predictors of 48mPSA; and (3) the prognostic utility of directional trends between PSA levels at 24
David J Handelsman
The Journal of clinical endocrinology and metabolism, 91(5), 1646-1653 (2006-02-16)
The objective of the study was to review the rationale underlying the banning of human chorionic gonadotropin (hCG) and estrogen blockers (antiestrogens, specific estrogen receptor modulators, aromatase inhibitors) in sports for male and female athletes in the light of gender
Y Zimmerman et al.
Human reproduction update, 20(1), 76-105 (2013-10-02)
BACKGROUND; Combined oral contraceptives (COCs) reduce levels of androgen, especially testosterone (T), by inhibiting ovarian and adrenal androgen synthesis and by increasing levels of sex hormone-binding globulin (SHBG). Although this suppressive effect has been investigated by numerous studies over many
E David Crawford et al.
Urology, 83(5), 1122-1128 (2014-03-26)
To demonstrate the safety and efficacy of up to 5 years of degarelix treatment and the effects of crossing over from leuprolide to degarelix in the extension phase of a phase III pivotal 1-year trial. Patients receiving degarelix who completed
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