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安全信息

34124

Supelco

脱氧雪腐镰刀菌烯醇 溶液

100 μg/mL in acetonitrile, analytical standard

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别名:
3a,7a,15-三羟基-12,13-环氧单端孢霉-9-烯-8-酮, DON, 呕吐毒素
经验公式（希尔记法）:
C15H20O6
CAS号:
51481-10-8
分子量:
296.32
EC 号:
200-835-2
MDL编号:
MFCD09039270
UNSPSC代码:
85151701
PubChem化学物质编号:
329754831
NACRES:
NA.24

等级

analytical standard

质量水平

100

保质期

limited shelf life, expiry date on the label

浓度

100 μg/mL in acetonitrile

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

cleaning products
cosmetics
food and beverages
personal care

格式

single component solution

储存温度

−20°C

SMILES字符串

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O

InChI

1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1

InChI key

LINOMUASTDIRTM-QGRHZQQGSA-N

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相关类别

一般描述

脱氧雪腐镰刀菌烯醇属于四环倍半萜类真菌毒素（称为单端孢霉烯），由镰刀菌真菌产生，天然存在于小粒谷物和感染的玉米中。

我们全系列的单端孢霉烯族真菌毒素标准物质。
脱氧雪腐镰刀菌烯醇常见于玉米、大麦、燕麦、黑麦、小麦、麦芽、面包、啤酒等谷物和农产品。它是一种霉菌毒素，主要通过减少农场动物的食物摄入量而影响畜牧业。谷物和其他食品中的DON污染是引发大骨节病（一种慢性和地方性骨关节病）的影响因素之一。

应用

有关合适的仪器技术的更多信息，请参阅产品′的分析证书。联系技术服务获得更多支持
脱氧雪腐镰刀菌烯醇可作为分析参考标准品，通过高效液相色谱-紫外检测法(HPLC-UV)对玉米粉和小麦粉基质中的分析物进行定量分析。它用作分析标准品，通过微阵列和生物信息学分析研究其对人软骨细胞的毒性作用机理。

象形图

FlameExclamation mark
GHS02,GHS07

警示用语：

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

WGK

WGK 2

闪点(°F)

closed cup

闪点(°C)

closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

高风险级别生物产品--毒素类产品
危险化学品

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

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Determination of 12 type A and B trichothecenes in cereals by liquid chromatography? electrospray ionization tandem mass spectrometry
Klotzel M, et al.
Journal of Agricultural and Food Chemistry, 53, 8904-8910 (2005)
Production of monoclonal antibodies for the specific detection of deoxynivalenol and 15-acetyldeoxynivalenol by ELISA
Sinha.CR, et al.
Journal of Agricultural and Food Chemistry, 43, 1740-1744 (1995)
Lei Yang et al.
Toxicology letters, 321, 61-68 (2019-12-22)
T-2 toxin and deoxynivalenol (DON) are two representative mycotoxins that are commonly found in cereals and agricultural products. As T-2 toxin and DON are considered the cause of Kashin-Beck disease, a special osteoarticular disease, chondrocytes would be a vital target
Giuseppina Avantaggiato et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(5), 817-824 (2004-03-30)
In vitro screening of 14 adsorbent materials, including some commercial products used to detoxify Fusarium-mycotoxins, were tested in the pH range of 3-8 for deoxynivalenol (DON)- and nivalenol (NIV)-binding ability. Only activated carbon showed to be effective with binding capacities
James J Pestka et al.
Journal of toxicology and environmental health. Part B, Critical reviews, 8(1), 39-69 (2005-03-15)
Deoxynivalenol (DON) is a mycotoxin that commonly contaminates cereal-based foods worldwide. At the molecular level, DON disrupts normal cell function by inhibiting protein synthesis via binding to the ribosome and by activating critical cellular kinases involved in signal transduction related
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