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Merck
CN

34124

脱氧雪腐镰刀菌烯醇 溶液

100 μg/mL in acetonitrile, analytical standard

别名:

3a,7a,15-三羟基-12,13-环氧单端孢霉-9-烯-8-酮, DON, 呕吐毒素

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关于此项目

经验公式（希尔记法）:
C15H20O6
化学文摘社编号:
51481-10-8
分子量:
296.32
NACRES:
NA.24
PubChem Substance ID:
329754831
UNSPSC Code:
85151701
EC Number:
200-835-2
MDL number:
MFCD09039270

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InChI key

LINOMUASTDIRTM-QGRHZQQGSA-N

InChI

1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1

SMILES string

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

Quality Level

100

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General description

脱氧雪腐镰刀菌烯醇属于四环倍半萜类真菌毒素（称为单端孢霉烯），由镰刀菌真菌产生，天然存在于小粒谷物和感染的玉米中。

我们全系列的单端孢霉烯族真菌毒素标准物质。
脱氧雪腐镰刀菌烯醇常见于玉米、大麦、燕麦、黑麦、小麦、麦芽、面包、啤酒等谷物和农产品。它是一种霉菌毒素，主要通过减少农场动物的食物摄入量而影响畜牧业。谷物和其他食品中的DON污染是引发大骨节病（一种慢性和地方性骨关节病）的影响因素之一。

Application

有关合适的仪器技术的更多信息，请参阅产品′的分析证书。联系技术服务获得更多支持
脱氧雪腐镰刀菌烯醇可作为分析参考标准品，通过高效液相色谱-紫外检测法(HPLC-UV)对玉米粉和小麦粉基质中的分析物进行定量分析。它用作分析标准品，通过微阵列和生物信息学分析研究其对人软骨细胞的毒性作用机理。

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

高风险级别生物产品--毒素类产品
危险化学品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCP3937
BCCN1430
BCCM7685
BCCM0159
BCCL6493

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Production of monoclonal antibodies for the specific detection of deoxynivalenol and 15-acetyldeoxynivalenol by ELISA
Sinha.CR, et al.
Journal of Agricultural and Food Chemistry, 43, 1740-1744 (1995)
Determination of 12 type A and B trichothecenes in cereals by liquid chromatography? electrospray ionization tandem mass spectrometry
Klotzel M, et al.
Journal of Agricultural and Food Chemistry, 53, 8904-8910 (2005)
Lei Yang et al.
Toxicology letters, 321, 61-68 (2019-12-22)
T-2 toxin and deoxynivalenol (DON) are two representative mycotoxins that are commonly found in cereals and agricultural products. As T-2 toxin and DON are considered the cause of Kashin-Beck disease, a special osteoarticular disease, chondrocytes would be a vital target
Giuseppina Avantaggiato et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(5), 817-824 (2004-03-30)
In vitro screening of 14 adsorbent materials, including some commercial products used to detoxify Fusarium-mycotoxins, were tested in the pH range of 3-8 for deoxynivalenol (DON)- and nivalenol (NIV)-binding ability. Only activated carbon showed to be effective with binding capacities
Sven Dänicke et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 60, 58-75 (2013-07-23)
The knowledge of factors influencing the kinetics, metabolism and bioavailability of the Fusarium toxin deoxynivalenol (DON) is a basic prerequisite for evaluation of the transfer (carry over) of the toxin and its metabolites into edible tissues, and for a physiological
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