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Merck
CN

34124

脱氧雪腐镰刀菌烯醇 溶液

100 μg/mL in acetonitrile, analytical standard

别名:

3a,7a,15-三羟基-12,13-环氧单端孢霉-9-烯-8-酮, DON, 呕吐毒素

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关于此项目

经验公式（希尔记法）:
C15H20O6
化学文摘社编号:
51481-10-8
分子量:
296.32
NACRES:
NA.24
PubChem Substance ID:
329754831
UNSPSC Code:
85151701
EC Number:
200-835-2
MDL number:
MFCD09039270

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产品名称

脱氧雪腐镰刀菌烯醇 溶液, 100 μg/mL in acetonitrile, analytical standard

InChI key

LINOMUASTDIRTM-QGRHZQQGSA-N

InChI

1S/C15H20O6/c1-7-3-9-14(5-16,11(19)10(7)18)13(2)4-8(17)12(21-9)15(13)6-20-15/h3,8-9,11-12,16-17,19H,4-6H2,1-2H3/t8-,9-,11-,12-,13-,14-,15+/m1/s1

SMILES string

CC1=C[C@H]2O[C@@H]3[C@H](O)C[C@@](C)([C@]34CO4)[C@@]2(CO)[C@H](O)C1=O

grade

analytical standard

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

single component solution

storage temp.

−20°C

Quality Level

100

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Application

有关合适的仪器技术的更多信息，请参阅产品′的分析证书。联系技术服务获得更多支持
脱氧雪腐镰刀菌烯醇可作为分析参考标准品，通过高效液相色谱-紫外检测法(HPLC-UV)对玉米粉和小麦粉基质中的分析物进行定量分析。它用作分析标准品，通过微阵列和生物信息学分析研究其对人软骨细胞的毒性作用机理。

General description

脱氧雪腐镰刀菌烯醇属于四环倍半萜类真菌毒素（称为单端孢霉烯），由镰刀菌真菌产生，天然存在于小粒谷物和感染的玉米中。

我们全系列的单端孢霉烯族真菌毒素标准物质。
脱氧雪腐镰刀菌烯醇常见于玉米、大麦、燕麦、黑麦、小麦、麦芽、面包、啤酒等谷物和农产品。它是一种霉菌毒素，主要通过减少农场动物的食物摄入量而影响畜牧业。谷物和其他食品中的DON污染是引发大骨节病（一种慢性和地方性骨关节病）的影响因素之一。

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

35.6 °F - closed cup

flash_point_c

2 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

高风险级别生物产品--毒素类产品
危险化学品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN1430
BCCM7685
BCCM0159
BCCL6493
BCCL3588

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Determination of 12 type A and B trichothecenes in cereals by liquid chromatography? electrospray ionization tandem mass spectrometry
Klotzel M, et al.
Journal of Agricultural and Food Chemistry, 53, 8904-8910 (2005)
Production of monoclonal antibodies for the specific detection of deoxynivalenol and 15-acetyldeoxynivalenol by ELISA
Sinha.CR, et al.
Journal of Agricultural and Food Chemistry, 43, 1740-1744 (1995)
Giuseppina Avantaggiato et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(5), 817-824 (2004-03-30)
In vitro screening of 14 adsorbent materials, including some commercial products used to detoxify Fusarium-mycotoxins, were tested in the pH range of 3-8 for deoxynivalenol (DON)- and nivalenol (NIV)-binding ability. Only activated carbon showed to be effective with binding capacities
Lei Yang et al.
Toxicology letters, 321, 61-68 (2019-12-22)
T-2 toxin and deoxynivalenol (DON) are two representative mycotoxins that are commonly found in cereals and agricultural products. As T-2 toxin and DON are considered the cause of Kashin-Beck disease, a special osteoarticular disease, chondrocytes would be a vital target
Dirk Rohweder et al.
Archives of animal nutrition, 67(1), 37-47 (2013-01-23)
Fusarium infections do not only affect the grain, but also the rest of the plant, which result in contamination of plants with the mycotoxin deoxynivalenol (DON). The bioavailability of DON may be influenced by the matrix due to the differences
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