33998
醋酸美伦孕酮
VETRANAL®, analytical standard
别名:
17α-乙酰氧基-6-甲基-16-亚甲基-4,6-孕甾二烯-3,20-二酮
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关于此项目
经验公式（希尔记法）:
C25H32O4
化学文摘社编号:
分子量:
396.52
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
220-859-7
Beilstein/REAXYS Number:
2066919
MDL number:
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
InChI
1S/C25H32O4/c1-14-11-19-20(23(5)9-7-18(28)13-21(14)23)8-10-24(6)22(19)12-15(2)25(24,16(3)26)29-17(4)27/h11,13,19-20,22H,2,7-10,12H2,1,3-6H3/t19-,20+,22+,23-,24+,25+/m1/s1
InChI key
UDKABVSQKJNZBH-DWNQPYOZSA-N
SMILES string
[H][C@]12CC[C@@]3(C)[C@@]([H])(CC(=C)[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C
grade
analytical standard
product line
VETRANAL®
shelf life
limited shelf life, expiry date on the label
mp
202-204 °C (lit.)
application(s)
clinical testing
format
neat
Quality Level
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General description
Melengestrol acetate belongs to the family of hormones. This acetylgestagen compound is known to elicit a gestagenic effect in vivo.
Application
Melengestrol acetate may be used as a reference standard for the determination of the analyte in:
- Milk using turborFlow online solid phase extraction (SPE) combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS).
- Kidney fats by ultra-performance convergence chromatography-tandem mass spectrometry.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Legal Information
VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
此项目有
Simultaneous determination of seven gestagens in kidney fats by Ultra Performance Convergence Chromatography tandem mass spectrometry.
Tao Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 988, 143-148 (2015)
Sarah Kelly Mortensen et al.
Analytica chimica acta, 586(1-2), 217-222 (2007-03-28)
A confirmatory method has been developed and validated for the determination of chlormadinone acetate (CMA), megestrol acetate (MGA), melengestrol acetate (MLA) and medroxyprogesterone acetate (MPA) in bovine and porcine plasma. Analytes are extracted from plasma samples using matrix-assisted liquid-liquid extraction
D A Mallory et al.
Journal of animal science, 88(11), 3568-3578 (2010-07-27)
Two experiments evaluated long-term progestin-based estrus-synchronization programs on the basis of potential for use in facilitating fixed-time AI in estrous cycling and prepubertal beef heifers. In Exp. 1, heifers were assigned to 1 of 2 treatments by age, BW, and
M E Corrigan et al.
Journal of animal science, 85(7), 1770-1779 (2007-03-21)
Previous research from our laboratory has indicated that melengestrol acetate (MGA) added to the diet during the first 35 d after arrival in the feedlot improves growth rates and tends to reduce chronic respiratory disease in heifers naturally challenged with
K Y Chung et al.
Journal of animal science, 87(12), 3897-3904 (2009-08-18)
Melengestrol acetate (MGA) has been used in the United States for nearly 40 yr to enhance feedlot heifer performance, yet unequivocal studies have not been conducted to discover the mechanism of action. Our hypothesis was that MGA may induce various
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