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等级
puriss. p.a.
质量水平
方案
≥98% (calc. to the dried substance)
表单
solid
杂质
≤0.002% heavy metals (as Pb)
灼烧残渣
≤0.1% (as SO4)
缺失
≤0.5% loss on drying, 105 °C
颜色
white to faint beige
mp
163-166 °C
164-166 °C (lit.)
痕量阴离子
chloride (Cl-): ≤100 mg/kg
sulfate (SO42-): ≤200 mg/kg
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
作用机制
DNA synthesis | interferes
enzyme | inhibits
SMILES字符串
Nc1ccc(cc1)S(N)(=O)=O
InChI
1S/C6H8N2O2S/c7-5-1-3-6(4-2-5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChI key
FDDDEECHVMSUSB-UHFFFAOYSA-N
基因信息
human ... CA1(759) , CA2(760) , CA5A(763) , CA5B(11238) , CA9(768)
mouse ... Car13(71934) , Car5a(12352)
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一般描述
化学结构：磺胺
磺胺（对氨基苯磺酰胺）是一种对氨基取代的苯磺酰胺。其邻-单和二碘衍生物已被合成。
应用
- Study of new azo-azomethine derivatives of sulfanilamide: synthesis, characterization, spectroscopic, antimicrobial, antioxidant and anticancer activity：通过生成重氮盐反应物并与2-羟基-3-甲氧基苯甲醛偶联制备对氨基苯磺酰胺的新衍生物，研究它们的潜在抗菌、抗氧化和抗癌活性(HS Al-Atbi, IJ Al-Assadi, et al., 2020)。
包装
33626-100G; 33626-6X100G
其他说明
保存于密闭容器内，置于干燥通风处。
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
The Iodination of p-Aminobenzenesulfonamide and Some Symmetrical Azobenzenesulfonamides.
Scudi JV.
Journal of the American Chemical Society, 59(8), 1480-1483 (1937)
Traci L Ness et al.
Journal of immunology (Baltimore, Md. : 1950), 173(11), 6938-6948 (2004-11-24)
CCR1 has previously been shown to play important roles in leukocyte trafficking, pathogen clearance, and the type 1/type 2 cytokine balance, although very little is known about its role in the host response during sepsis. In a cecal ligation and
Caroline A Dobbin et al.
Journal of immunology (Baltimore, Md. : 1950), 169(2), 958-965 (2002-07-05)
We propose that the 70-kDa heat shock protein (HSP70) protects virulent Toxoplasma gondii from the effects of the host by immunomodulation. This hypothesis was tested using quercetin and antisense oligonucleotides targeting the start codon of the virulent T. gondii HSP70
Joseph A Hollenbaugh et al.
Journal of immunology (Baltimore, Md. : 1950), 177(5), 3004-3011 (2006-08-22)
We previously reported that IFN-gamma secreted by donor cytotoxic T cell 1 (Tc1) cells was the most important factor in promoting EG7 (an OVA transfection the EL4 thymoma) rejection in mice. In this study, we show that the ability of
Edward E Knaus et al.
Bioorganic & medicinal chemistry letters, 21(19), 5892-5896 (2011-08-20)
A series of compounds incorporating regioisomeric phenylethynylbenzenesulfonamide moieties has been investigated for the inhibition of four human carbonic anhydrase (hCA, EC 4.2.1.1) isoforms, hCA I, II, IX and XII. Inhibition between the low nanomolar to the milliomolar range has been
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