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Our anhydrous solvents deliver exceptionally low water content, making them the ideal choice for moisture-sensitive laboratory applications. Packaged in the exclusive Sure/Seal^™ septum bottle system, they are reliably protected against moisture ingress from first use to last drop. The innovative Sure/Seal^™ closure combines an advanced plug-style liner with an airtight elastomer and crimp cap design to ensure consistent product integrity. Three unique liner materials provide optimal chemical compatibility across a broad range of solvents. Sure/Seal^™ packaging is proven to maintain anhydrous conditions even after repeated punctures. With more than 70 products across all major solvent families, available in pack sizes from 100 mL to 2 L, the portfolio meets virtually every laboratory need. By choosing ready-to-use anhydrous solvents in Sure/Seal^™ packaging, researchers eliminate the need for time-consuming and hazardous in-house solvent drying and distillation - saving time, reducing risk, and improving reproducibility.

We are committed to bringing you Greener Alternative Products that adhere to one of the four categories of Greener Alternatives. Propylene Carbonate is an enabling product used to synthesize lithium-ion batteries with improved electrical conductivity, promoting energy efficiency and enhancing overall battery performance. Click here for more information.

Anhydrous solvents in Sure/Seal^™ packaging are essential wherever water contamination would compromise experimental results. They are widely used in moisture-sensitive applications such as organic synthesis - including Grignard reactions, organometallic chemistry, and catalysis - as well as in peptide, oligonucleotide, and pharmaceutical synthesis.

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC