生物来源
rabbit
质量水平
抗体形式
diluted serum
抗体产品类型
primary antibodies
克隆
polyclonal
形式
liquid
包含
≤0.1% sodium azide as preservative
种属反应性
rat
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
avoid repeated freeze/thaw cycles
同位素/亚型
IgG
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
Rattus norvegicus ... Slc1A2(29482)
一般描述
Anti-Excitatory Amino Acid Transporter (GLT-1), rabbit polyclonal recognizes the ~75 kDa and the ~50 kDa forms of GLT-1. It is validated for use in Western blotting and immunoprecipitation.
Rabbit polyclonal antibody supplied as diluted serum. Recognizes the ~75 kDa and the ~50 kDa forms of GLT-1.
Recognizes the ~75 kDa and the ~50 kDa forms of GLT-1.
免疫原
a synthetic peptide (NGKSADCSVEEEPWKREK) corresponding to amino acids at the C-terminus of rat GLT-1
警告
Toxicity: Standard Handling (A)
其他说明
Arriza, J.L., et al. 1997. Proc. Natl. Acad. Sci. USA94, 4155.
Nagao, S., et al. 1997. Neuroscience78, 929.
Rothstein, J.D., et al. 1995. Ann. Neurol.14, 5559.
Arriza, J.L., et al. 1994. J. Neurosci.14, 5559.
Rothstein, J.D., et al. 1993. Proc. Natl. Acad. Sci. USA90, 6591.
Kanai, Y., et al. 1992. Nature360, 467.
Pines, G., et al. 1992. Nature360, 464.
Rothstein, J.D., et al. 1992. N. Engl J. Med.326, 1464.
Storck T., et al. 1992. Proc. Natl. Acad. Sci. USA89, 10955.
Nagao, S., et al. 1997. Neuroscience78, 929.
Rothstein, J.D., et al. 1995. Ann. Neurol.14, 5559.
Arriza, J.L., et al. 1994. J. Neurosci.14, 5559.
Rothstein, J.D., et al. 1993. Proc. Natl. Acad. Sci. USA90, 6591.
Kanai, Y., et al. 1992. Nature360, 467.
Pines, G., et al. 1992. Nature360, 464.
Rothstein, J.D., et al. 1992. N. Engl J. Med.326, 1464.
Storck T., et al. 1992. Proc. Natl. Acad. Sci. USA89, 10955.
This antibody may also cross react nonspecifically with a ~102 kDa protein not believed to be related to GLT-1. This antibody has also been reported to work for immunoprecipitation. Antibody should be titrated for optimal results in individual systems.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
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WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Christian M Cremer et al.
Epilepsia, 51(8), 1446-1455 (2010-04-14)
The astrocytic enzyme glutamine synthetase (GS) is a key regulator of glutamate and γ-aminobutyric acid (GABA) metabolism in the glutamate/glutamine cycle (GGC). Inhibition of GS results in changes of neurotransmitter release and recycling. However, little is known about the influence
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