推荐产品
生物来源
mouse
质量水平
抗体形式
culture supernatant
抗体产品类型
primary antibodies
克隆
M2 I-4, monoclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
wet ice
基因信息
human ... ABCC2(1244)
特异性
This antibody reacts with an internal epitope of MRP2, a 190-200 kDa transmembrane protein previously known as the canalicular multi-organic anion transporter (cMOAT). MRP2 is a member of the MRP family of multidrug resistance related proteins, and MRP2 overexpression has been observed in a subset of cisplatin resistant cell lines. This antibody does not cross-react with the human MDR1, MRP1, MRP3 or MRP5 gene products.
免疫原
Fusion protein of MRP2 containing aa 215-310 of the protein.
应用
This Anti-MRP2 Antibody, clone M2 I-4 is validated for use in WB, IC, IH for the detection of MRP2.
Western blotting: 1:20 - 1:50 with anti-mouse HRP
Immunocytochemistry: 1:20 - 1:50 on acetone fixed cytospin preparations
Immunohistochemistry: 1:20 on acetone fixed frozen tissue sections
Optimal working dilutions must be determined by end user.
Immunocytochemistry: 1:20 - 1:50 on acetone fixed cytospin preparations
Immunohistochemistry: 1:20 on acetone fixed frozen tissue sections
Optimal working dilutions must be determined by end user.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
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Chunying Li,John D Schuetz,Anjaparavanda P Naren
Cancer letters null
M Kummu et al.
Placenta, 33(10), 859-865 (2012-08-16)
Heavy metals such as cadmium, lead and methylmercury are known to be neurotoxic to developing fetus. ABCG2 which is an efflux transporter located in the maternal facing membranes of human placenta protects fetus from xenobiotics by transferring compounds from syncytiotrophoblast
C C Paulusma et al.
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The human Dubin-Johnson syndrome and its animal model, the TR(-) rat, are characterized by a chronic conjugated hyperbilirubinemia. TR(-) rats are defective in the canalicular multispecific organic anion transporter (cMOAT), which mediates hepatobiliary excretion of numerous organic anions. The complementary
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