biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
181-15A12, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... MMP13(4322)
Application
Anti-MMP-13 Antibody, clone 181-15A12 detects level of MMP-13 & has been published & validated for use in ELISA, WB, IH(P).
Immunoblotting
Immunohistochemistry on paraffin-embedded tissue sections.
Immunohistochemistry on paraffin-embedded tissue sections.
Research Category
Cell Structure
Cell Structure
Research Sub Category
MMPs & TIMPs
MMPs & TIMPs
Biochem/physiol Actions
Reacts with precursor and active forms of human MMP-13 and does not cross-react with human MMP-1, 2, 3, 7, 8, 9. This is a purified mouse moncolonal antibody to recombinant human matrix metalloproteinase 13 (human MMP-13, procollagenase-3).
Physical form
Format: Purified
Purified immunoglobulin to recombinant human matrix metalloproteinase 13 (human MMP-13, procollagenase-3). Liquid in 0.1 M PBS, pH 7.0 containing 4% protease free bovine serum albumin.
Preparation Note
Maintain at -20°C for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Manufactured by Daiichi Fine Chemical Co., Ltd
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Development of a solid-phase assay for analysis of matrix metalloproteinase activity.
Lauer-Fields, JL; Nagase, H; Fields, GB
Journal of biomolecular techniques : JBT null
M R Junttila et al.
Oncogene, 26(36), 5267-5279 (2007-03-06)
Recent studies indicate that the specificity of p38 mitogen-activated protein kinase (MAPK)-mediated cellular stress responses is determined by the expression pattern of the distinct p38 isoforms. Here, we have analysed the function of distinct p38 isoforms in the growth and
Jorge González-Zamora et al.
Antioxidants (Basel, Switzerland), 12(4) (2023-04-28)
Age-related macular degeneration (AMD) is a leading cause of severe vision loss in older individuals in developed countries. Despite advances in our understanding of AMD, its pathophysiology remains poorly understood. Matrix metalloproteinases (MMPs) have been proposed to play a role
J M Del Casar et al.
Breast cancer research and treatment, 116(1), 39-52 (2009-02-26)
An immunohistochemical study was performed using tissue arrays and specific antibodies against MMPs -1, -2, -7, -9, -11, -13, -14, and TIMPs -1, -2 and -3. More than 5,000 determinations on cancer specimens from 124 patients with invasive breast cancer
Elizabeth H Stephens et al.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society, 13(6), 447-458 (2010-06-12)
At birth, the mechanical environment of valves changes radically as fetal shunts close and pulmonary and systemic vascular resistances change. Given that valves are reported to be mechanosensitive, we investigated remodeling induced by perinatal changes by examining compositional and structural
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