产品名称
Anti-Fibronectin Antibody, cell binding peptide, clone 784A2A6, purified antibody, clone 784A2A6, Chemicon®
biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
784A2A6, monoclonal
species reactivity
human, chicken
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable, western blot: suitable
isotype
IgG1
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
chicken ... Fn1(396133)
human ... FN1(2335)
Immunogen
Epitope: cell binding peptide
Human plasma fibronectin.
Application
Anti-Fibronectin Antibody, cell binding peptide, clone 784A2A6 detects level of Fibronectin & has been published & validated for use in ELISA & WB.
ELISA
Microscopy
Western blotting at 1-5 μg/mL
Cellular Adhesion Studies
Note: Dilution without addition of carrier protein may cause denautration or adherence of the antibody to the vial. Dilution into a 1% bovine serum albumin containing buffer is recommended.
Optimal working dilutions must be determined by end user.
Microscopy
Western blotting at 1-5 μg/mL
Cellular Adhesion Studies
Note: Dilution without addition of carrier protein may cause denautration or adherence of the antibody to the vial. Dilution into a 1% bovine serum albumin containing buffer is recommended.
Optimal working dilutions must be determined by end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
ECM Proteins
ECM Proteins
Biochem/physiol Actions
Reacts with the 11kd cell adhesive fragment and weakly inhibits cell binding to fibronectin (fibronectin mediated cell adhesion).
Physical form
Liquid in 0.02M Phosphate buffer, 0.25M NaCl with 0.1% sodium azide.
Preparation Note
Maintain at 2-8°C for up to 6 months in undiluted aliquots
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
存储类别
12 - Non Combustible Liquids
Souhaila Ghadhab et al.
Journal of biomedical materials research. Part A, 109(11), 2187-2198 (2021-05-02)
Intraosseous transcutaneous amputation prosthesis is a new approach in orthopedic implants that overcomes socket prosthesis problems. Its long-term performance requires a tight skin-implant seal to prevent infections. In this study, fibronectin (Fn), a widely used adhesion protein, was adsorbed or
S Kim et al.
The Journal of biological chemistry, 275(43), 33920-33928 (2000-08-17)
Recent studies indicate that angiogenesis depends, in part, on ligation of integrin alpha(5)beta(1) by fibronectin. Evidence is now provided that integrin alpha(5)beta(1) regulates the function of integrin alpha(v)beta(3) on endothelial cells during their migration in vitro or angiogenesis in vivo.
Helena P Felgueiras et al.
Langmuir : the ACS journal of surfaces and colloids, 30(31), 9477-9483 (2014-07-24)
Functionalization of surfaces with poly(sodium styrenesulfonate) (poly(NaSS)) has recently been found to enhance osteointegration of implantable materials. Radical polymerization of poly(NaSS) on titanium (Ti)-based substrates has been used to improve their long-term performance by preventing fibrosis and consequently implant loosening.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAB1934 | 04053252665707 |