产品名称
Anti-Laminin γ1 Antibody, clone 2E8, ascites fluid, clone 2E8, Chemicon®
antibody form
ascites fluid
biological source
mouse
conjugate
unconjugated
antibody product type
primary antibodies
clone
2E8, monoclonal
species reactivity
rat, human
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
cell culture | mammalian: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... LAMC1(3915)
Analysis Note
Control
Basement membrane, Hippocampal tissue
Basement membrane, Hippocampal tissue
Application
ELISA (50% maximal binding to human laminin): (1:300,000.
Immunofluorescence
Affinity chromatography
Immunoprecipitation
Immunoblotting
Optimal working dilutions must be determined by end user.
Immunofluorescence
Affinity chromatography
Immunoprecipitation
Immunoblotting
Optimal working dilutions must be determined by end user.
This Anti-Laminin γ1 Antibody, clone 2E8 is validated for use in ELISA, CULT, IH, IP, WB for the detection of Laminin γ1.
Biochem/physiol Actions
Reacts with the B2 chain of intact human laminin and does not block the neurite stimulating activity of laminin. Cross reacts with the 200 kDa chain of rat laminin.
General description
200 kDa
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Liquid, no preservatives added.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Bicuspid aortic valve aortopathy is characterized by embryonic epithelial to mesenchymal transition and endothelial instability.
Freiholtz, et al.
Journal of molecular medicine (Berlin, Germany), 101, 801-811 (2023)
CARDIOVASCULAR RISK FACTORS AFFECT HIPPOCAMPAL MICROVASCULATURE IN EARLY AD.
Schwartz, E; Wicinski, B; Schmeidler, J; Haroutunian, V; Hof, PR
Translational neuroscience null
Steven D Funk et al.
Journal of the American Society of Nephrology : JASN, 29(3), 949-960 (2017-12-22)
Pierson syndrome is a congenital nephrotic syndrome with eye and neurologic defects caused by mutations in laminin β2 (LAMB2), a major component of the glomerular basement membrane (GBM). Pathogenic missense mutations in human LAMB2 cluster in or near the laminin
Tina Nybo et al.
Redox biology, 20, 496-513 (2018-11-27)
Basement membranes are specialized extracellular matrices that underlie arterial wall endothelial cells, with laminin being a key structural and biologically-active component. Hypochlorous acid (HOCl), a potent oxidizing and chlorinating agent, is formed in vivo at sites of inflammation via the
Activation and localization of matrix metalloproteinase-2 and -9 in the skeletal muscle of the muscular dystrophy dog (CXMDJ).
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BMC Musculoskelet. Disord. null
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