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Merck
CN

HCYTA-60K-PX48

MILLIPLEX®人细胞因子/趋化因子/生长因子组合A 48 Plex预混合磁珠试剂盒-免疫学多重分析

Premixed Human Cytokine/Chemokine/Growth Factor 48-Plex Panel A

别名:

Human cytokine multiplex kit, Luminex® human cytokine immunoassay, Millipore human cytokine panel

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NACRES:
NA.77
UNSPSC Code:
12161503
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产品名称

MILLIPLEX®人细胞因子/趋化因子/生长因子组合A 48 Plex预混合磁珠试剂盒-免疫学多重分析, Premixed Human Cytokine/Chemokine/Growth Factor 48-Plex Panel A

Quality Level

species reactivity

human

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

technique(s)

multiplexing: suitable

input

cell culture supernatant
serum

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze 48 analytes in human serum, plasma, and cell culture supernatants.Analytes included: sCD40L, EGF, Eotaxin/CCL11, FGF-2/FGF-basic, FLT-3L, Fractalkine/CX3CL1, G-CSF, GM-CSF, GROα, IFNα2, IFNγ, IL-1α, IL-1β, IL-1RA, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, IL-10, IL-12 (p40), IL-12(p70), IL-13, IL-15, IL-17A/CTLA8, IL-17E/IL-25, IL-17F, IL-18, IL-22, IL-27, IP-10/CXCL10, MCP-1/CCL2, MCP-3/CCL7, M-CSF, MDC, MIG/CXCL9, MIP-1α/CCL3, MIP-1β/CCL4, PDGF-AA, PDGF-AB/BB, RANTES/CCL5, TGFα, TNFα, TNFβ/LTA, VEGF-ANote: RANTES cannot be plexed with other cytokines in this panel due to a required 1:100 dilution of plasma/serum samples. This premixed panel comes with a RANTES bead, so please plan your samples accordingly.Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Lead the Field with 48-Plex Precision: The ability to profile 48 analytes simultaneously means researchers can uncover intricate cytokine interactions and pathways that are essential for understanding complex diseases.Confidence in Results with Cross-Reactivity Testing: Enhanced verification means you can publish your findings with greater assurance, knowing that your data is backed by thorough testing protocols.Disease Profiling Power: Proven utility in profiling immune responses in cancer, sepsis, IBD, and autoimmune diseases. Detects subtle changes in cytokine levels across disease states.High Biological Relevance: Analytes selected for their roles in inflammation, immune regulation, angiogenesis, and cell signaling, including key biomarkers like IL-6, TNFα, IL-10, VEGF-A, and PDGF-BB.Peer-Reviewed Validation: Extensively cited in immunology and disease research publications. Trusted by academic and clinical researchers worldwide.

General description

Cytokines, chemokines, and growth factors are key mediatorsof immune system functions capable of signaling through autocrine, paracrine,and endocrine mechanisms. Their pleiotropic immunomodulatory propertiesallow these biomolecules to react to diverse stimuli and regulate the immuneresponse, either promoting or inhibiting inflammation.

signalword

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

存储类别

10 - Combustible liquids

法规信息

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Igor V Kudryavtsev et al.
Viruses, 14(9) (2022-09-24)
The adaptive antiviral immune response requires interaction between CD8+ T cells, dendritic cells, and Th1 cells for controlling SARS-CoV-2 infection, but the data regarding the role of CD8+ T cells in the acute phase of COVID-19 and post-COVID-19 syndrome are
Kuo-Chu Lai et al.
Journal of cachexia, sarcopenia and muscle, 13(2), 1314-1328 (2022-02-17)
Interferon-induced protein with tetratricopeptide repeat 2 (IFIT2) is a reported metastasis suppressor in oral squamous cell carcinoma (OSCC). Metastases and cachexia may coexist. The effect of cancer metastasis on cancer cachexia is largely unknown. We aimed to address this gap
Austen Terwilliger et al.
Viruses, 13(10) (2021-10-27)
We rationally designed a bacteriophage cocktail to treat a 56-year-old male liver transplant patient with complex, recurrent prostate and urinary tract infections caused by an extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli (E. coli) (UCS1). We screened our library for phages that
Xianwen Ren et al.
Cell, 184(7), 1895-1913 (2021-03-04)
A dysfunctional immune response in coronavirus disease 2019 (COVID-19) patients is a recurrent theme impacting symptoms and mortality, yet a detailed understanding of pertinent immune cells is not complete. We applied single-cell RNA sequencing to 284 samples from 196 COVID-19
Luis G Gómez-Escobar et al.
Scientific reports, 11(1), 12606-12606 (2021-06-17)
Increasing evidence has shown that Coronavirus disease 19 (COVID-19) severity is driven by a dysregulated immunologic response. We aimed to assess the differences in inflammatory cytokines in COVID-19 patients compared to contemporaneously hospitalized controls and then analyze the relationship between

相关内容

Cytokine multiplex assays allow researchers to easily investigate the immune system. The MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Multiplex Panels A and B are multiplex assays for cytokine detection that each offer a unique combination of 48 analytes that can be simultaneously analyzed in a small sample volume.

See how a MILLIPLEX® multiplex cytokine assay demonstrated superior lot-to-lot consistency of cytokine measurement in human serum and plasma samples when compared to other Luminex® technology-based multiplex assays.

See how MILLIPLEX® multiplex cytokine panels can be used in alternate sample types such as human tears, urine, milk, saliva, and CSF with an example of characterizing neuroinflammation across healthy, MCI, and AD CSF samples.

MILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panels A and B offer customizable options for analyzing nearly 100 cytokines.

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